R.N. MAMLEEV^1, 2, E.V. LUCHKINA², I.G. ANDREEVA²

 ¹Kazan State Medical University, Kazan

²Children’s Republican Clinical Hospital, Ministry of Health of Republic of Tatarstan, Kazan

  Contact details:

Mamleev R.N. — PhD (medicine), Associate Professor of Department of Hospital Pediatrics

Address: 49 Butlerov St., Russian Federation, Kazan, 420012, tel.: +7-917-921-12-70, e-mail: [email protected]

The wrong choice of starting antibiotic is one of the reasons for therapeutic failure in the treatment of acute otitis media in children. Currently, in Russia and around the world, macrolides are frequently used — drugs with low activity against Streptococcus pneumoniae. Prescription of macrolides in otiatrics is associated with the fear of allergies to β-lactam antibiotics (penicillins, cephalosporins), but this fear is highly hypertrophied and true anaphylaxis is extremely rare. Most often, there is a phenomenon of quasiallergy — a skin rash that is not associated with an allergy to an antibiotic. A detailed allergological history and the use of a proven algorithm of antibiotic therapy allow avoiding unnecessary frequent prescribing of macrolides and provide effective control over the focus of infection.

Key words: children, acute otitis media, antibiotics, anaphylaxis, quasiallergy, medical errors.