S.N. NAVRUZOV, R.V. KHAYRUTDINOV, D.A. PULATOV, L.T. ALIMKHODZHAEVA, B.B. USMANOV

Republican Cancer Research Center of the Ministry of Health of the Republic of Uzbekistan, 383 Pharobi St., Tashkent, Republic of Uzbekistan, 100095

Navruzov S.N. — D. Med. Sc., Professor, Head of the Republican Cancer Research Center of the Ministry of Health of the Republic of Uzbekistan, tel. (99871) 227-13-27, e-mail: [email protected]

Khayrutdinov R.V. — D. Med. Sc., Scientific Director of Thoracic Oncology Department, tel. (99894) 380-01-40, е-mail: [email protected]

Pulаtov D.A. — D. Med. Sc., Scientific Director of Chemotherapy Department, tel. (99891) 190-59-40, е-mail: [email protected]

Alimkhodzhaeva L.T. — D. Med. Sc., Scientific Director of Oncomammology Department, tel. (99890) 348-17-30, e-mail: [email protected]

Usmanov B.B. — doctor of Thoracic Oncology Department, tel. (99894) 604-52-15, e-mail: [email protected], [email protected]

The frequency of breast cancer metastasis to the lung and pleura and its determinants. There was made a comparative analysis of long-term results of complex treatment of patients with breast cancer. The main group included 30 patients, lungs and pleura metastases developed within a 5 year follow-up period; the control group included 30 patients with no relapses and metastases over the same period. A set of factors have been identified which significantly effect (either way) the probability of development of lung and pleura metastases. These findings help to assess in a comprehensive and exhausting way the probability of metastasizing of the primary tumor without any additional expensive techniques.

Key words: breast cancer, metastases in the lungs and pleura, prognosis factors.

 

 

REFERENCES

1. Blinov N.N. Prognostic factors in oncology. Voprosy onkologii, 2001, no. 47 (3), pp. 369-72 (in Russ.).

2. Moiseenko V.M., Semiglazov V.V., Tyulyandin S.A. Sovremennoe lekarstvennoe lechenie mestno-rasprostranennogo i metastaticheskogo raka molochnoy zhelezy [Modern drug therapy for locally advanced and metastatic breast cancer]. Saint Petersburg: Grifon, 1997. 254 p.

3. Sedykh S.A. Diagnosis of metastatic lung tumors. Rossiyskiy onkologicheskiy zhurnal, 1997, no. 5, pp. 20-6 (in Russ.).

4. Semiglazov V.F. Prognostic value and predicting factors when choosing a treatment for patients with breast cancer metastatic. Prakticheskaya onkologiya, 2000, no. 2, pp. 26-30 (in Russ.).

5. Kharchenko V.P., Gurevich L.A. et al. Computed tomography with solitary metastases to the lungs. Voprosy onkologii, 1999, no. 1, pp. 29-34 (in Russ.).

6. Chissov V.I., Trakhtenberg A.Kh., Pikin O.V. et al. Metastaticheskie opukholi legkikh [Metastatic lung tumors]. Moscow: GEOTAR-Media, 2009.

7. Gantsev Sh.Kh. New to the theory of cancer metastasis and approaches to its treatment. Kreativnaya khirurgiya i onkologiya, 2010, no. 4, pp. 5-11 (in Russ.).

8. Bozhok A.A., Semiglazov V.F., Semiglazov V.V. et al. Prognostic factors in breast cancer. Sovremennaya onkologiya, 2005, no. 1, pp. 46-49 (in Russ.).

9. Ganul V.L., Bororov L.V, Ganul A.V. et al. Feasibility of surgical removal of metastases of malignant tumors in the lungs. Klinicheskaya onkologiya, 2012, no. 5 (1), pp. 18-20 (in Russ.).