S.N. NAVRUZOV, R.V. KHAYRUTDINOV, D.A. PULATOV, L.T. ALIMKHODZHAEVA, B.B. USMANOV

Republican Cancer Research Center of the Ministry of Health of the Republic of Uzbekistan, 383 Pharobi St., Tashkent, Republic of Uzbekistan, 100095

Navruzov S.N. — D. Med. Sc., Professor, Head of the Republican Cancer Research Center of the Ministry of Health of the Republic of Uzbekistan, tel. (99871) 227-13-27, e-mail: [email protected]

Khayrutdinov R.V. — D. Med. Sc., Scientific Director of Thoracic Oncology Department, tel. (99894) 380-01-40, е-mail: [email protected]

Pulаtov D.A. — D. Med. Sc., Scientific Director of Chemotherapy Department, tel. (99891) 190-59-40, е-mail: [email protected]

Alimkhodzhaeva L.T. — D. Med. Sc., Scientific Director of Oncomammology Department, tel. (99890) 348-17-30, e-mail: [email protected]

Usmanov B.B. — doctor of Thoracic Oncology Department, tel. (99894) 604-52-15, e-mail: [email protected], [email protected]

The frequency of breast cancer metastasis to the lung and pleura and its determinants. There was made a comparative analysis of long-term results of complex treatment of patients with breast cancer. The main group included 30 patients, lungs and pleura metastases developed within a 5 year follow-up period; the control group included 30 patients with no relapses and metastases over the same period. A set of factors have been identified which significantly effect (either way) the probability of development of lung and pleura metastases. These findings help to assess in a comprehensive and exhausting way the probability of metastasizing of the primary tumor without any additional expensive techniques.

Key words: breast cancer, metastases in the lungs and pleura, prognosis factors.

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