V.M. GAZIZYANOVA, O.V. BULASHOVA, E.V. KHAZOVA, V.N. OSLOPOV

Kazan State Medical University of the Ministry of Health of the Russian Federation, Kazan

  Contact:

Gazizyanova V.M. ― PhD (medicine), Associate Professor of the Department of Propedeutic Internal Diseases named after S.S. Zimnitskiy

Address: 49 Butlerov Str., Kazan, Russian Federation, 420012, e-mail: sunny.gazizyanova@list.ru

Today multiple morbidity is characteristic for patients with chronic cardiac failure (CCF), which contributes to the course of the main and the accompanying disease and significantly worsens the prognosis, resulting in large social-economic losses.

The objective is to research the yearly prognosis for CCF combined with chronic obstructive pulmonary disease.

Material and methods. The research included 183 patients with CCF, of them 105 ‒ CCF combined with chronic obstructive pulmonary disease. All patients underwent the following examinations: walk test, scoring the clinical condition, external breathing function test with spirometry, standard echocardiography, life quality assessment.

Results. Patients with CCF combined with chronic obstructive pulmonary disease (COPD) were characterized by high smoking rate, low quality of life and low tolerance to physical load. Cardiovascular death rate in CCF combined with COPD was 4.0%, not differing significantly from that in CCF without COPD ― 4.6%; myocardial infarction was 1.7 more frequent in CCF combined with COPD than in patients with CCF without COPD (16.8% and 10.8%); stroke was observed only in CCF combined with COPD (8.9%). Combined end point (all cardiovascular events) in comorbid pathology was 2.3 more frequent that in patients with CCF only (29.7% and 15.4%). Hospitalization due to acute decompensation of CCF was 2 times more frequent in the group with comorbid pathology (CCF and COPD), that without it (32.7% and 15.4%).

Conclusion. The research results showed that chronic obstructive pulmonary disease contributes a lot to the clinical variant of CCF, which significantly aggravates the prognosis and requires an integral approach to the treatment tactics and stratification of the risk of undesired events.

Key words: prognosis, chronic obstructive pulmonary disease, chronic heart failure.

(For citation: Gazizyanova V.M., Bulashova O.V., Khazova E.V., Oslopov V.N. Predicting the course of chronic cardiac failure combined with chronic obstructive pulmonary disease. Practical medicine. 2020. Vol. 18, №1, P. 65-69)

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