M.A. KUTLUBAEV^1,2, V.D. MENDELEVICH³, L.R. AKHMADEEVA²

¹Republican Clinical Hospital named after G.G. Kuvatova, 132 Dostoevskiy St., Ufa, Russian Federation, 450005

²Bashkir State Medical University, 3 Lenin St., Ufa, Russian Federation, 450000

³Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

Kutlubaev M.A. — Cand. Med. Sc., physician of a Neurology Department, Assistant of the Department of Neurology with courses of Neurosurgery and Medical Genetics, tel. (347) 228-75-00, e-mail: [email protected]

Mendelevich V.D. — D. Med. Sc., Professor, Head of the Department of Medical and General Psychology, tel. (843) 238-60-74, e-mail: [email protected]

Akhmadeeva L.R. — D. Med. Sc., Professor at the Department of Neurology with courses of Neurosurgery and Medical Genetics, tel. (347) 272-56-64, email: [email protected]

Within one month after stroke 227 people were examined for post-stroke fatigue phenomenon (PSF), had a comparative assessment of the frequency and correlations of PSF and similar phenomena (apathy, depression). Symptoms of PSF have been identified in 46.7% of patients, while the frequency of depression and apathy was approximately 20%. In 21% of patients PSF developed independently, in other cases — in conjunction with apathy and / or depression. Development of PSF was associated with strokes in the vertebrobasilar system, female sex, and the presence of acute or uncompensated chronic somatic pathology. Development of apathy is correlated with signs of chronic structural brain damage and depression — with the severity of neurologic deficit. Therefore, PSF is low-specific, heterogeneous phenomenon which may occur in connection with lesions of certain cerebral structures, as well as in other neuropsychiatric and somatic stroke complications. On this basis, it is proposed to divide PSF on primary, secondary and associated with abnormal fatigue.

Key words: psychoneurological disorders, fatigue, asthenia, apathy, depression, stroke.

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