N.E. AFANASIEV¹, O.YU. POZDNYAKOVA²

 ¹City Clinical Polyclinic No. 5, Stavropol

²Stavropol State Medical University, Stavropol

 Contact details:

Afanasiev N.E. — PhD (medicine), therapist

Address: 15 Zarechniy proyezd, Stavropol, Russian Federation, 355026, tel.: +7-928-813-70-88, e-mail: dvamedika03@yandex.ru

A retrospective analysis of medical documents of 735 patients with exacerbation of chronic obstructive pulmonary disease in round-the-clock hospitals in the Shpakovsky district of the Stavropol Territory was carried out. The sensitivity of the main bacterial pathogens of the disease such as Streptococcus pneumonia, Staphylococcus aureus, Haemophilus influenza and Enterobacteriacea was determined in a third of patients. The search for epidemiologically significant pathogens of the respiratory tract infectious pathology, such as Mycoplasma pneumoniae, Сhlamydia pneumoniae, was not carried out during the analyzed period. The wrong choice of starting antibiotic therapy was made in 45% of cases. Estimation of the effectiveness of antibiotic therapy was revised in less than 33.5% of hospitalized patients. Broncholytic and anti-inflammatory therapy did not correspond to the severity of the disease in 39.2% of patients. The identified problems of therapy in patients with chronic obstructive pulmonary disease led to long periods of hospitalization and increase in health care costs.

Key words: chronic obstructive pulmonary disease, antibacterial therapy, resistance, exacerbation.

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