Meningitis in infants
Kh.S. KHAYERTYNOV1, R.I. MINGAZHEVA2, L.M. ZIYATDINOVA3, E.Yu. ALATYREV2, G.I. GABDULLINA1
1Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420124
2Republican Clinical Hospital of Infectious Diseases, 83 Prospekt Pobedy, Kazan, Russian Federation, 420140
3Children’s Republican Clinical Hospital, 140 Orenburgskiy trakt, Kazan, Russian Federation, 420138
Khaertynov Kh.S. — Cand. Med. Sc., Associate Professor of the Department of Children’s Infectious Diseases, tel.: (843) 555-04-65, +7-903-342-96-27, e-mail: khalit65l@rambler.ru
Mingazheva R.I. — Head of Resuscitation Department, tel.: (843) 267-80-02, +7-917-231-56-32, e-mail: rianna.83@mail.ru
Ziyatdinova L.M. — Head of Insulation and Diagnostic Department, (843) 237-31-75, e-mail: L.Ziyatdinova@tatar.ru
Alatyrev E.Yu. — Head of Resuscitation Department, tel.: (843) 555-57-28, +7-903-313-84-54, e-mail: alatyreff.zhenya2012@yandex.ru
Gabdullina G.I. — student of Pediatric Faculty, tel. +7-960-046-92-27, e-mail: gulnaz.gabdullina.91@mail.ru1
The clinical and epidemiological characteristics of the course of meningitis in young children were studied with the account of the disease etiology. The most frequent causes of meningitis were St.pneumoniae and H.influenzae. Almost one third of cases developed into serous meningitis. Stiff neck was noted only in 76% of cases. Despite the dominance of bacteria in the etiological structure of meningitis in infants, as well as long duration of the disease, in most cases there was a favorable outcome. Mortality among patients under observation was 4%.
Key words: meningitis, children, early age.
REFERENCES
1. V.P. Novelli, M. Peters, Dobson S. «Infectious diseases» in Care of the Critically Ill Child, A.J. Macnab, D.J. Macrae and R. Henning, Eds., Churchill Livingstone, London, UK. 1999. Pp. 281-298.
2. Edmond K., Clark A., Korczak V.S., Sanderson C., Griffiths U.K., Rudan I. Global and regional risk of disabling sequelae from bacterial meningitis: a systematic review and meta-analysis. The Lancet Infectious Diseases, 2010, vol. 10, no. 5, pp. 317-328.
3. Susana Cha´vez-Bueno, George H. McCracken. Bacterial Meningitis in Children. Pediatr Clin N Am., 2005, no. 52, rr. 795-810.
4. Catherine L. Tacon, Oliver Flower. Diagnosis and Management of Bacterial Meningitis in the Paediatric Population: A Review. Emergency Medicine International, 2012. Article ID 320309. R. 8.
5. WHO, «Bacterial Meningitis», New and Under-utilized Vaccines Implementation (NUVI), 2010, available at: http://www.who.int/nuvi/meningitis/en/index.html.
6. Rabab Z Jafri, Asad Ali, Nancy E Messonnier, Carol Tevi-Benissan, David Durrheim, Juhani Eskola, Florence Fermon, Keith P Klugman, Mary Ramsay, Samba Sow, Shao Zhujun, Zulfiqar A Bhutta and Jon Abramson. Global epidemiology of invasive meningococcal disease. Population Health Metrics, 2013, 11:17, p. 2, available at: http://www.pophealthmetrics.com/content/11/1/17
7. Kharlamova F.S. Meningococcal disease in children. Lechashchiy vrach, 2008, no. 1 (in Russ.).
8. Brouwer M.C., Tunkel A.R. D. van de Beek. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clinical Microbiology Reviews, 2010, vol. 23, no. 3, pp. 467-492.
9. Klein J.O. Bacterial meningitis and sepsis, in Remington JS, Klein JO (eds): Infectious Disease of the Fetus and Newborn Infant. Philadelphia: WB Saunders. 2000. Pp. 943-98.
10. Reefhuis J., Honein M.A., Whitney C.G. et al. Risk of bacterial meningitis in children with cochlear implants. The New England Journal of Medicine, 2003, vol. 349, no. 5, pp. 435-445.
11. Saez-Llorens X.M. and X. M. GH. Acute bacterial meningitis beyond the neonatal period in Long: Principles and Practice of Pediatric Infectious Diseases Revised Reprint, S. Long, Ed. Churchill Livingstone, Philadelphia, Pa, USA, 3rd edition. 2008. Pp. 284-291.
12. Vincent J. Quagliarello, W. Michael Scheld. Treatment of Bacterial Meningitis. N Engl J Med., 1997, 336. Rr. 708-716.