A.V. TKACHEV ¹, L.S. MKRTCHYAN ¹, K.E. MAZOVKA ¹, Т.А. DEVLIKAMOVA ², V.I. KONONENKO ², E.V. NEYKOVSKAYA ²

 ¹ Rostov State Medical University of the Ministry of Health of the Russian Federation, 29 Nakhichevanskiy Alley, Rostov-on-Don, Russian Federation 344022

² City Hospital No. 20, 39 Kommunisticheskiy Alley, Rostov-on-Don, Russian Federation, 344091

 Contact details:

Tkachev A.V. — D. Med. Sc., Professor, Head of the Department of Propaedeutics of Internal Diseases, e-mail: [email protected]

Mkrtchyan L.S. — teaching assistant of the Department of Propaedeutics of Internal Diseases, tel.  (863) 271-97-05, e-mail: [email protected]

Mazovka K.E. — Cand. Med. Sc., Assistant of the Department of Propaedeutics of Internal Diseases, tel. (863) 271-97-05, e-mail: [email protected]

Devlikamova T.A. — Cand. Med. Sc., Head of the Therapeutic Department, tel. (863) 271-97-00, e-mail: [email protected]

Kononenko V.I. — Cand. Med. Sc., Head of the Department of Maxillofacial Surgery and Surgical Stomatology, tel. (863) 2719681, e-mail: [email protected]

Neykovskaya E.V. — Doctor of the Department of Maxillofacial Surgery and Surgical Stomatology, tel. (863) 271-96-81, e-mail: [email protected]

Received: March 5, 2018, accepted for printing: April 13, 2018

 Practicing physician often faces difficulties in differential diagnosis of diseases relating to the interface between rheumatology and gastroenterology, which is associated with the similarity of pathogenetic mechanisms of autoimmune pathology. This article is devoted to the features of the lesion of the mucous membranes of the oral cavity and the gastrointestinal tract in Behcet’s disease, in contrast to ulcerative colitis.

 Key words: aphthous stomatitis, ulcerative colitis, Behcet’s disease.

 (For citation: Tkachev A.V., Mkrtchyan L.S., Mazovka K.E., Devlikamova T.A., Kononenko V.I., Neykovskaya E.V. Medical crime story: differential diagnosis of autoimmune lesions of the gastrointestinal tract in the practice of a multi-speciality hospital doctor. Practical medicine. 2018)

REFERENCES

1. Revmatologiya: klinicheskie rekomendatsii, pod red. akad. RAMN E.L. Nasonova. 2-e izd., ispr. i dop. [Rheumatology: clinical recommendations. Ed. by acad. RAMS E.L. Nasonov. 2 nd ed., Rev. and additional]. Moscow: GEHOTAR-Media, 2010. 752–754 p.
2. Revmatologiya: natsionalʹnoe rukovodstvo, pod red. akad. RAMN E.L. Nasonova. 2-e izd., ispr. i dop. [Rheumatology: national leadership. Ed. by acad. RAMS E.L. Nasonov. 2 nd ed., Rev. and additional]. Moscow: GEHOTAR-Media, 2008. 721 p.
3. Hatemi G., Silman A., Bang D., Bodaghi B., Chamberlain A.M., Gul A., Houman M.H., Kötter I., Olivieri I., Salvarani C., Sfikakis P.P., Siva A., Stanford M.R., Stübiger N., Yurdakul S., Yazici H. EULAR recommendations for the management of Behçet disease. Ann. Rheum. Dis., 2008, vol. 67(12), pp. 1656–62.
4. Direskeneli H. Behçet’s disease: infectious aetiology, new autoantigens, and HLA-B51. Annals of the rheumatic diseases, 2001, vol. 60, no. 11, pp. 996–1002.