O.I. PIKUSA, E.A. SAMORODNOVA

Kazan State Medical University, Kazan

 Contact details:

Pikusa O.I. — MD, Professor of the Department of Propaedeutics of Children’s Diseases and Faculty Pediatrics

Address: 49 Butlerov St., Russian Federation, Kazan 420012, tel.: +7-917-390-11-12, e-mail: [email protected]

The purpose — to present the information on the main causes of lymphadenopathies in children and the stages of differential-diagnostic search which complicate diagnosing and determining the treatment tactics.

Material and methods. Analysis of literature data on lymphadenopathies in children, features of clinical manifestations under tumorous and non-tumorous etiology of the disease, and approaches to differential diagnostics.

Results. The article presents the general information on etiology and classification of the characteristic clinical symptoms of lymphadenopathies in children, which are necessary for a pediatrician to determining the treatment tactics of a patient with this pathology.

Conclusion. For duly diagnosing a child with lymphadenopathy, a pediatrician should be aware of a wide range of nosologies and be attentive to any detail of the case history, clinical picture and laboratory examination data, as it may influence not only the treatment efficiency but even life forecast for the patient.

Key words: children, lymphadenopathies, glands, diagnostics.

REFERENCES

1. Natsional’nye klinicheskie rekomendatsii po diagnostike limfadenopatiy, 2018 [National clinical guidelines for the diagnosis of lymphadenopathies, 2018], available at: https://npngo.ru/uploads/media_document/281/1f167737-5f09-47d7-a25b-c43b0cfe916e.pdf
2. Klinicheskie rekomendatsii «Limfadenopatii u vzroslykh», 2014 (Natsional’noe gematologicheskoe obshchestvo) [Clinical guidelines «Lymphadenopathy in adults», 2014 (National Hematological Society)], available at: https://docplayer.ru/113748510-Limfadenopatii-u-vzroslyh.html
3. Naumova A.S., Tiganova O.A., Il’enko L.I. Peripheral lymphadenopathy in children: an oncologist’s view. Moskovskaya meditsina, 2020, no. 1 (35), pp. 57–63 (in Russ.).
4. Miranovich S.I., Cherchenko N.N., Glinnik A.V., Samsonov S.V. Differential diagnosis of lymphadenopathies of the maxillofacial region. Sovremennaya stomatologiya, 2018, no. 1, pp. 9–14 (in Russ.).
5. Tereshchenko S.Yu. Generalized lymphadenopathy of infectious etiology in children: issues of differential diagnosis. Russkiy meditsinskiy zhurnal. Meditsinskoe obozrenie, 2013, vol. 21, no. 3, pp. 129–133 (in Russ.).
6. Tereshchenko S.Yu. Peripheral lymphadenopathy in children: differential diagnosis. Consilium Medicum, Pediatriya, 2011, no. 4, pp. 54–59 (in Russ.).
7. Mishin K.I., Naletov A.A. Lymphadenopathies in children: differential diagnosis. Akademicheskiy zhurnal Zapadnoy Sibiri, 2019, vol. 15, no. 5 (82), pp. 46–48 (in Russ.).
8. Ozhegov A.M. Differential diagnosis of lymphadenopathies in children. Prakticheskaya meditsina, 2013, no. 6 (75), pp. 49–58 (in Russ.).
9. Mohseni S., Shojaiefard A., Khorgami Z., Alinejad S., Ghorbani A., Ghafouri A. Peripheral lymphadenopathy: approach and diagnostic tools. Iran J Med Sci, 2014, Mar, vol. 39 (2), pp. 158–170.
10. King D., Ramachandra J., Yeomanson D. Lymphadenopathy in children: refer or reassure? Arch Dis Child Educ Pract Ed, 2014, vol. 99, pp. 101–110.
11. Shamanskaya T.V., Kachanov D.Yu. Lymphadenopathies in children. Praktika pediatra, 2008, no. 3, pp. 54–58 (in Russ.).
12. Locke R., Comfort R., Kubba H. When does an enlarged cervical lymph node in a child need excision? A systematic review. Int J Pediatr Otorhinolaryngol, 2014, vol. 78 (3), pp. 393–401.
13. Twist C.J., Link M.P. Assessment of lymphadenopathy in children. Pediatr Clin North Am, 2002, vol. 49, pp. 1009–1025.
14. Gaddey H.L., Riegel A.M. Unexplained lymphadenopathy: evaluation and differential diagnosis. Am Fam Physician, 2016, vol. 94 (11), pp. 896–903.
15. Nield L.S., Kamat D. Lymphadenopathy in children: when and how to evaluate. Clin Pediatr, 2004, vol. 43, pp. 25–33.
16. Sahai S. Lymphadenopathy. Pediatrics in Rev, 2013, vol. 34, pp. 216.
17. Melikyan A.L. Algoritmy diagnostiki limfadenopatiy. Programmnoe lechenie zabolevaniy sistemy krovi [Algorithms for the diagnosis of lymphadenopathies. Programmed treatment of diseases of the blood system]. Moscow, 2012. Pp. 417–152.