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  • Justification of choice of etiotropic drug for flu in children on the basis of the principles of evidence-based medicine

    Редактор | 2016, Original articles, Practical medicine 08 (16) Pediatrics | 30 ноября, 2016

    E.S. GASILINA, O.V. BORISOVA, L.P. MATVEEVA, N.M. BOCHKAREV, N.P. KABANOVA, N.S. POLEZHAEVA, A.A. FRANK

    Samara State Medical University, 89 Chapaevskaya Str., Samara, Russian Federation, 443099

    Gasilina E.S. ― D. Med. Sc., Professor, Head of the Department of Children’s Infections, tel. (846) 994-75-38, e-mail: gasilinaes@mail.ru

    Borisova O.V. ― D. Med. Sc., Professor of the Department of Children’s Infections, tel. (846) 333-30-86, e-mail: olgaborisova74@mail.ru

    Matveeva L.P. ― postgraduate student of the Department of Children’s Infections, tel. (846) 994-75-38, e-mail: gasilinaes@mail.ru

    Bochkareva N.M. ― Cand. Med. Sc., Assistant of the Department of Children’s Infections, tel. (846) 994-75-38, e-mail: nat.177@mail.ru

    Kabanova N.P. ― Cand. Med. Sc., Associate Professor of the Department of Children’s Infections, tel. (846) 994-75-38, e-mail: nat.177@mail.ru

    Polezhaeva N.S. ― Cand. Med. Sc., Associate Professor of the Department of Children’s Infections, tel. (846) 994-75-38, e-mail: natali146@list.ru

    Frank A.A. ― Senior Laboratory worker of the Department of Children’s Infections, tel. (846) 994-75-38, e-mail: frankan@rambler.ru

     The article presents a retrospective analysis of the effectiveness of three groups of antiviral drugs, used in the treatment of flu in children in hospital. Evaluation of the results of treatment was conducted in 82 children with a confirmed diagnosis of influenza, using the principles of evidence-based medicine, using special mathematical data processing ― the fourfold tables.

    Key words: antiviral drugs; treatment of acute viral respiratory infection and influenza in children; comparative effectiveness.

    REFERENCES

    1. Malyy V.P., Andreychin M.A. Gripp (sezonnyy, ptichiy, pandemicheskiy) i drugie ORVI [Influenza (seasonal, avian, pandemic) and other acute respiratory viral infections]. Moscow: GEOTAR-Media, 2012. 320 p.
    2. Mitrofanov A.V. et al. The problem of the choice of antiviral drug for the treatment of infectious mononucleosis in children. Prakticheskaya meditsina, 2012, no. 7-1 (63), p. 62 (in Russ.).
    3. Tyutyunik L.P. Comparative evaluation of the effectiveness of antiviral drugs of different groups of children with SARS in outpatient settings. Aspirantskiy vestnik Povolzh’ya, 2014, no. 1-2, pp. 149-151 (in Russ.).
    4. Uchaykin V.F. Obosnovanie, opyt lecheniya i profilaktika ostrykh respiratornykh virusnykh infektsiy preparatami rekombinantnogo interferona: metod. rekomendatsii [The rationale, experience of treatment and prophylaxis of acute respiratory viral infections drugs recombinant interferon: method. Recommendations]. Moscow: Spetskniga, 2012. 48 p.
    5. Khenegan K., Badenoch D. Dokazatel’naya meditsina [Evidence-Based Medicine]. Moscow: GEOTAR-Media, 2011. 144 p.
    6. Shpigel’ A.S., Greshnova Z.A. The therapeutic effects of Traumeel S in the treatment of keloids. Biologicheskaya meditsina, 2010, no. 1, pp. 30-34 (in Russ.).

    Метки: 2016, A.A. FRANK, antiviral drugs; treatment of acute viral respiratory infection and influenza in children; comparative effectiveness, E.S. GASILINA, L.P. MATVEEVA, N.M. BOCHKAREV, N.P. KABANOVA, N.S. POLEZHAEVA, O.V. BORISOVA, Practical medicine 08 (16) Pediatrics

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