S.V. KHALIULLINA¹, V.A. ANOKHIN¹, M.SH. GALIULLINA², K.R. SALAKHOVA¹, A.D. KISLICYNA¹

 ¹Kazan State Medical University, Kazan

²Republican Clinical Hospital for Infectious Diseases named after A.F. Agafonov, Kazan

Contact details:

Khaliullina S.V. — MD, Associate Professor of the Department of Pediatric Infections

Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7 (843) 267-80-06, e-mail: svekhal@mail.ru

 The incidence of COVID-19 is growing worldwide, despite the enormous efforts made by the health authorities, scientific medical community, and medical practitioners. Since the disease is «new», the results of any research related to the epidemiology, diagnosis, treatment, prevention of the disease, and even individual interesting clinical cases are important. We present an intrafamilial case of SARS-CoV-2 infection in three generations of the same family. Of interest, in this case, are the features of the clinical symptoms of COVID-19 when infected with one virus, in almost the same living conditions, but in different age groups. Three patients (the youngest in the family) had a mild infection, one in a moderate form, and two (the oldest generation) in a severe one; their response to pathogenetic therapy was different. Our clinical example once again demonstrates the heterogeneity of the clinical picture of the new coronavirus infection, even in identical living conditions and a single source of infection. Knowledge of risk factors, correct interpretation of the results of laboratory and instrumental studies, an integrated approach to treatment should increase the therapy effectiveness in such patients.

Key words: COVID-19, SARS-CoV-2, coronavirus infection, pandemic, intrafamilial infection, clinical course.

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