L.I. MALTSEVA¹, E.N. VASILYEVA^2,3, T.G. DENISOVA^2,3, Yu.V. GARIFULLOVA⁴

 ¹Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan

²Chuvash State University named after I.N. Ulyanov, Cheboksary

³Institute for Doctors’ Advanced Education, Cheboksary

⁴Kazan State Medical University of the Ministry of Health of the Russian Federation, Kazan

Contact:

Maltseva L.I. — MD, Professor of the department of Obstetrics and Gynecology

Address: 36 Butlerov Str., 420012, Kazan, Russian Federation, tel. +7-905-314-40-51, e-mail: [email protected]

The article presents analysis of literature data on the relation between vitamin D provision and pregnancy course in women. The authors emphasize high frequency of vitamin D deficit in pregnant women living in various latitudes, and its adverse influence on health during pregnancy. Blood serum level of 25OHD<32 ng/ml increases the risk of preeclampsia, gestation diabetes mellitus in mother and pre-mature births, increases the frequency of cesarean section and bacterial vaginosis; leads to low weight of a fetus and a newborn, to inhibition of hip growth in a fetus, impaired cardial function in babies, craniotabes, acute infection of lower respiratory tract, and hypocalcaemia. The recommended doses of vitamin D are analyzed to prevent severe complications of pregnancy. Conclusion is made about the need to correct efficiency or insufficiency of vitamin D in blood serum up to its optimal level of 40 ng/ml, which ensured favorable course of pregnancy.

Key words: vitamin D, 25(OH)D, pregnancy, complications of pregnancy, preeclampsia, gestation diabetes mellitus, fetus growth inhibition.

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