Yu.E. TEREGULOV^1,2, Z.K. LATIPOVA², M.S. MAKSIMOVA¹, N.V. MAKSUMOVA¹

¹ KSMA –– Branch Campus of the FSBEI FPE RMACPE MOH Russia, 36 Butlerov Str., Kazan, Russian Federation, 420012

² Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012

Teregulov Yu. E. — D. Med. Sc., Associate Professor, Head of the Department of Functional Diagnostics, Associate Professor of the Department of Hospital Therapy, tel. +7-917-264-70-04, e-mail: [email protected]

Latipova Z.K. ― applicant of the Department of Hospital Therapy, tel. +7-987-285-33-52, e-mail: [email protected]

Maksimova M.S. ― Assistant Lecturer of the Department of Functional Diagnostics, tel. +7-917-393-05-19, e-mail: [email protected]

Maksumova N.V. ― Assistant Lecturer of the Department of Functional Diagnostics, tel.  +7-917-257-80-03, e-mail: [email protected]

The article is devoted to the study of the influence of integral indices of central hemodynamics and structural-geometric remodeling of the left ventricle on the daily profile of arterial pressure in senior patients with arterial hypertension (AH). 75 patients aged from 60 to 86 y.o. (68.6 ± 6.9) were examined; of them 45 women (60 %) and 30 men (40 %). All patients underwent 24-hour monitoring of blood pressure (BP) and echocardiography. The 24-hour patterns of BP, heart rate, SV, CO, systolic and diastolic BP were determined. According to the mathematical model, modulus of volume elasticity (MVE), total peripheral vascular resistance (TPVR), MVE/TPVR and mean arterial pressure were calculated. The geometric model of LV remodeling and the differentiated types of hemodynamic were determined. It is shown that the increase in the integral stiffness of the arterial system and the overall peripheral vascular resistance, together with the decrease in the shock release contribute to the lower degree of nocturnal decrease in systolic blood pressure in patients with AH. Most frequently, night pressure is increases under hyperkinetic type of circulation and in patients with predominant stiffness of the arterial system.The types of 24-hour pattern of BP for eccentric and concentric types of structural-geometric remodeling of the left ventricle in patients with AH are presented.

Key words: daily monitoring of arterial blood pressure, central hemodynamics, geometric remodeling of the left ventricle, arterial hypertension.

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