Influence of correction of sleep disorders on the effectiveness of rehabilitation in patients after stroke
E.V. KOSTENKO1,2, S.N. BOBYREVA2
1Pirogov Russian National Research Medical University, 1 Ostrovityanova Str., Moscow, Russian Federation, 117997
2Moscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports Medicine of the Department of Health of Moscow, 21 Verkhnyaya Krasnoselskaya Str., Moscow, Russian Federation, 107140
Kostenko E.V. ― D. Med. Sc., Professor of the Department of neurology and neurosurgery of the medical faculty of Pirogov Russian National Research Medical University, leading researcher of Moscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports Medicine of the Department of Health of Moscow, e-mail: Ekostenko58@mail.ru
Bobyreva S.N. ― Deputy head of the branch №7 of Moscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports Medicine of the Department of Health of Moscow
The purpose of research ― to study efficiency of correction of sleep disorders by Melaksen® taking into account the level of secretion of melatonin (6-SOMT) at patients with stroke.
Material and methods. The study included 141 patients with CVD. Examination of patients included assessment of neurological status, psychometric scales, the definition of circadian rhythm of the heart and blood pressure, determination of 6-SOMT in urine.
Results. It was found that pathological changes in circadian rhythms affect sleep disturbances, emotional and cognitive disorders and are associated with a reduction in the level of 6-SOMT in the urine. These changes are most pronounced in patients with stroke. The efficiency of inclusion in a comprehensive rehabilitation regimen Melaxen® in respect of sleep disorders.
Conclusion. The data obtained allow us to consider Melaxen® as an effective tool in the complex rehabilitation of patients with cerebrovascular diseases.
Key words: insomnia, circadian rhythms, rehabilitation, stroke, Melaxen.