V.F. EKGARDT¹, K.N. DASHENKO²

¹South-Ural State Medical University, 64 Vorovskogo Str., Chelyabinsk, Russian Federation, 454092

²City Clinical Hospital №11, 17a Dzerzhinskogo Str., Chelyabinsk, Russian Federation, 454129

Ekgardt V.F. ― D. Med. Sc., Professor of the Department of Ophthalmology, tel. +7-904-817-12-06, e-mail: anita1@inbox.ru

Dashenko K.N. ― physician, tel. +7-904-817-12-06, e-mail: k.dashenko@mail.ru

Dynamic observation of patients with nonproliferative diabetic retinopathy on the background of diabetes mellitus type 2 within 3 years after laser treatment has allowed to set decrease in the amplitude of the b-wave and increase indicators of latency of electroretinography, while prescription of fenofibrates eliminates the negative effect of laser photocoagulation on retina.

Key words: diabetic retinopathy, laser retinal photocoagulation, phenofibrate.

REFERENCES

1. Dedov I.I., Shestakova M.V. Diabetes mellitus — a global medical and social problem of our time. Consilium medicum, 2009, 11, 12, pp. 5-8 (in Russ.).
2. American Diabetes Association: Standarts of medical care in diabetes-2011. Diabetes Care, 2011, 34, suppl 1, pp. 4-88.
3. Astakhov Yu.S., Shadrichev F.E., Lisichkina A.B. Diabeticheskaya retinopatiya/klinicheskie rekomendatsii [Diabetic retinopathy, clinical guidelines]. Oftal’mologiya. Moscow, 2006: GOETAR-Media, 2006. P. 178.
4. Lipatov A.V., Chistyakov T.A., Kuz’min A.G., Tolkacheva A.A. Evaluating the effectiveness of drug therapy Ganfort in patients with secondary neovascular glaucoma in diabetes. Vestnik oftal’m, 2014, vol. 130, no. 3, pp. 45-46 (in Russ.).
5. Skorobogatova E.S., Libman E.S. Dinamika invalidnosti po zreniyu vsledstvie sakharnogo diabeta v Rossii. Dinamika invalidnosti po zreniyu vsledstvie sakharnogo diabeta v Rossii [The dynamics of disability-free as a result of diabetes in Russia]. Sovremennye vozmozhnosti v diagnostike i lechenii vitreoretinal’noy patologii. Moscow, 2004. Pp. 307-310.
6. Izmaylov A.C. Diabeticheskaya retinopatiya i makulyarnpyy otek (diagnostika i lazernoe lechenie): avtoref. dis. … d-ra med. nauk [Diabetic retinopathy and makulyarnpy edema (diagnostics and laser treatment). Synopsis of dis. Dr med. sciences]. Saint Petersburg, 2004. P. 46.
7. Izmaylov A.C., Balashevich L.I. Klinicheskaya klassifikatsiya diabeticheskoy makulopatii [Clinical classification of diabetic maculopathy]. Sovremennye tekhnologii lecheniya vitreoretinal’noy patologii: sb. nauch. st. Moscow, 2002. Pp. 123-127.
8. Olevskaya E.A. Diabeticheskaya makulopatiya: klinika, prognoz razvitiya, differentsirovannyy podkhod k lecheniyu: avtoref. dis. … kand. med. nauk [Diabetic maculopathy: clinical, development outlook, a differentiated approach to the treatment of. Synopsis of dis. PhD med. sciences]. Chelyabinsk, 2004. P. 24.
9. Neubauer A.S., Ulbig M.W. Laser treatment in diabetic retinopathy. Ophthalmologica, 2007,vol. 221, rr. 95-102.
10. Tang L.P., Feng H.Y. Therapeutic effect of argon green laser for diabetic retinopathy. Di Yi Jun Yi Da Xue Xue Bao, 2004, Dec, 24 (12), pp. 1452-1454.
11. Basinskaya L.A. Comprehensive treatment for diabetic retinopathy. Klinicheskaya oftal’mologiya, 2006, no. 3, pp. 95-97 (in Russ.).
12. Ekgardt V.F. Kliniko-immunologicheskie aspekty patogeneza, diagnostiki i lecheniya diabeticheskoy retinopatii: avtoref. dis. … d -ra med. nauk [Clinical and immunological aspects of pathogenesis, diagnosis and treatment of diabetic retinopathy. Synopsis of dis. PhD med. sciences]. Chelyabinsk, 1997. P. 42 .
13. Zueva M.V. Fundamental ophthalmology: the role of electrophysiological studies. Vestnik oftal’mologii, 2014, vol. 130, no. 6, pp. 30-31 (in Russ.).
14. Mansurina N.B., Arakelyan M.A., Shamshinova A.M. Bioelektricheskaya aktivnost’ setchatki pri diabeticheskoy makulopatii [Bioelectric activity of the retina in diabetic maculopathy]. Aktual’nye problemy oftal’mologii 2008/ Sbornik nauchnykh rabot pod red. Kh.P. Takhchidi. Moscow, 2009. Pp. 198-199.
15. Neroev V.V., Kolchin A.A., Zueva M.V., Kiseleva T.N. et al. Association disorders of retinal functional activity, metabolic and hemodynamic changes in patients with diabetes without signs of retinopathy. Rossiyskiy oftal’mologicheskiy zhurnal, 2013, 6 (1), pp. 20-25 (in Russ.).
16. Shamshinova A.M. Elektroretinografiya v oftal’mologii [Electroretinography in ophthalmology]. Moscow: Medika, 2009. Pp. 232-242.
17. Tyrberg M., Ponjavic V., Lovestam-Adrian M. Multifocal electroretinogram (mfERG) in patients with diabetes mellitus and an enlarged foveal avascular zone (FAZ). Documenta Ophthalmologica, 2008, Nov, 117 (3), pp. 185-189.