N.V. RYLOVA¹, A.V. ZHOLINSKY²

¹Kazan State Medical University of the Ministry of Health of the Russian Federation, Kazan

²Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of the FMBA of Russia, Moscow

Contact:

Rylova N.V. — MD, Professor of the Department of Hospital Pediatrics with a course in Polyclinic Pediatrics

Address: 49 Butlerov Str., 420012, Kazan, Russian Federation, tel. (843) 221-24-28, e-mail: rilovanv@mail.ru

The complex relationship between gut microbiota and behavior has attracted increasing attention in recent years. Altered cognitive function is considered as a component of many pathological conditions, including metabolic and intestinal diseases. The role of microbiota in modulating these diseases can be of great clinical importance. Studies of the interaction between factors that modulate the intestinal microbiota and their subsequent effect on cognitive function are in the process of accumulating data. Although the exact mechanism underlying the influence of microbiota on cognitive functions remains to be confirmed, modern hypotheses focus on the interaction of the nervous, endocrine and immune factors. Identification of possible neuronal and humoral relationships involved in the regulation of the “microbiota-intestines-brain” axis requires further study.

Key words: microbiota, intestines, «microbiota-intestines-brain axis», cognitive functions.

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