E.N. SHAKHBAZOVA¹, E.N. ZHAD’KO¹, E.Yu. KOTLYAR¹, O.S. ZAKHAROVA¹, L.N. KILINA¹, F.N. NAGIMOVA¹, N.I. GALIULLIN¹, M.P. SHULAYEVA², O.K. POZDEYEV^2,3

¹Republic Center for PreventionandCountercation to AIDS and Infectious Diseases, 2a Vishnevskiy St., Kazan, Russian Federation, 420097

²Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012

³Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

Shakhbazova E.N. — Head of Microbiology Laboratory, tel. (843) 238-41-81, e-mail: lenashakhbazova@yandex.ru¹

Zhad’ko E.N. — bacteriologist, tel. (843) 238-41-81 e-mail: centre_spid@tatar.ru¹

Kotlyar E.Yu. — Cand. Biol. Sc., bacteriologist, tel. (843) 238-41-81, e-mail: centre_spid@tatar.ru¹

Zakharova O.S. — bacteriologist, tel. (843) 238-41-81, e-mail: centre_spid@tatar.ru¹

Kilina L.N. — Deputy Chief Doctor, tel. (843) 238-77-04, e-mail: centre_spid@tatar.ru¹

Nagimova F.I. — Cand. Med. Sc., Deputy Chief Doctor, tel. (843) 238-19-06, e-mail: centre_spid@tatar.ru¹

Galiullin N.I. — Cand. Med. Sc., Chief Doctor, tel. (843) 238-19-06, e-mail: centre_spid@tatar.ru¹

Shulayeva M.P. — Cand. Biol. Sc., Associate Professor of the Department of icrobiology, tel. (843) 233-34-78, e-mail: shulaeva.m@mail.ru²

Pozdeyev O.K. — D. Med. Sc., Professor, Head of the Department of Microbiology of KSMA and KSMU, tel. (843) 233-34-78, e mail: pozdeevoskar@rambler.ru^2,3

The article presents the results of a survey of 103 HIV-infected patients. The considered issues are the mycological research of all patients with clinical diagnosis of meningitis and meningoencephalitis. The characteristic is presented of bacterioscopic, strain and immunological methods of research of the clinical material obtained from patients, namely CSF and serum. New data are obtained of the selection pathogenic fungus of Cryptococcus from HIV-infected patients. Frequency of Cryptococcus allocation is associated with age and sex of patients, as well as with the clinical pattern of the disease. The role of cryptococcosis as AIDS-marking disease is proved. The monitoring of the antimycotics sensitivity was held when choosing the Cryptococcus treatment.

Key words: Сryptococcus, cerebrospinal fluid, serum, HIV-infected, antifungal preparations.

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