First cases of Cryptococcus in Tatarstan Republic
E.N. SHAKHBAZOVA1, E.N. ZHAD’KO1, E.Yu. KOTLYAR1, O.S. ZAKHAROVA1, L.N. KILINA1, F.N. NAGIMOVA1, N.I. GALIULLIN1, M.P. SHULAYEVA2, O.K. POZDEYEV2,3
1Republic Center for PreventionandCountercation to AIDS and Infectious Diseases, 2a Vishnevskiy St., Kazan, Russian Federation, 420097
2Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012
3Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012
Shakhbazova E.N. — Head of Microbiology Laboratory, tel. (843) 238-41-81, e-mail: lenashakhbazova@yandex.ru1
Zhad’ko E.N. — bacteriologist, tel. (843) 238-41-81 e-mail: centre_spid@tatar.ru1
Kotlyar E.Yu. — Cand. Biol. Sc., bacteriologist, tel. (843) 238-41-81, e-mail: centre_spid@tatar.ru1
Zakharova O.S. — bacteriologist, tel. (843) 238-41-81, e-mail: centre_spid@tatar.ru1
Kilina L.N. — Deputy Chief Doctor, tel. (843) 238-77-04, e-mail: centre_spid@tatar.ru1
Nagimova F.I. — Cand. Med. Sc., Deputy Chief Doctor, tel. (843) 238-19-06, e-mail: centre_spid@tatar.ru1
Galiullin N.I. — Cand. Med. Sc., Chief Doctor, tel. (843) 238-19-06, e-mail: centre_spid@tatar.ru1
Shulayeva M.P. — Cand. Biol. Sc., Associate Professor of the Department of icrobiology, tel. (843) 233-34-78, e-mail: shulaeva.m@mail.ru2
Pozdeyev O.K. — D. Med. Sc., Professor, Head of the Department of Microbiology of KSMA and KSMU, tel. (843) 233-34-78, e mail: pozdeevoskar@rambler.ru2,3
The article presents the results of a survey of 103 HIV-infected patients. The considered issues are the mycological research of all patients with clinical diagnosis of meningitis and meningoencephalitis. The characteristic is presented of bacterioscopic, strain and immunological methods of research of the clinical material obtained from patients, namely CSF and serum. New data are obtained of the selection pathogenic fungus of Cryptococcus from HIV-infected patients. Frequency of Cryptococcus allocation is associated with age and sex of patients, as well as with the clinical pattern of the disease. The role of cryptococcosis as AIDS-marking disease is proved. The monitoring of the antimycotics sensitivity was held when choosing the Cryptococcus treatment.
Key words: Сryptococcus, cerebrospinal fluid, serum, HIV-infected, antifungal preparations.
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