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  • First cases of Cryptococcus in Tatarstan Republic

    Редакция | 2014, Original articles, Practical medicine 07 (14) Infectious diseases. Antimicrobial therapy | 7 октября, 2014

    E.N. SHAKHBAZOVA1, E.N. ZHAD’KO1, E.Yu. KOTLYAR1, O.S. ZAKHAROVA1, L.N. KILINA1, F.N. NAGIMOVA1, N.I. GALIULLIN1, M.P. SHULAYEVA2, O.K. POZDEYEV2,3

    1Republic Center for PreventionandCountercation to AIDS and Infectious Diseases, 2a Vishnevskiy St., Kazan, Russian Federation, 420097

    2Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012

    3Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

    Shakhbazova E.N. — Head of Microbiology Laboratory, tel. (843) 238-41-81, e-mail: lenashakhbazova@yandex.ru1

    Zhad’ko E.N. — bacteriologist, tel. (843) 238-41-81 e-mail: centre_spid@tatar.ru1

    Kotlyar E.Yu. — Cand. Biol. Sc., bacteriologist, tel. (843) 238-41-81, e-mail: centre_spid@tatar.ru1

    Zakharova O.S. — bacteriologist, tel. (843) 238-41-81, e-mail: centre_spid@tatar.ru1

    Kilina L.N. — Deputy Chief Doctor, tel. (843) 238-77-04, e-mail: centre_spid@tatar.ru1

    Nagimova F.I. — Cand. Med. Sc., Deputy Chief Doctor, tel. (843) 238-19-06, e-mail: centre_spid@tatar.ru1

    Galiullin N.I. — Cand. Med. Sc., Chief Doctor, tel. (843) 238-19-06, e-mail: centre_spid@tatar.ru1

    Shulayeva M.P. — Cand. Biol. Sc., Associate Professor of the Department of icrobiology, tel. (843) 233-34-78, e-mail: shulaeva.m@mail.ru2

    Pozdeyev O.K. — D. Med. Sc., Professor, Head of the Department of Microbiology of KSMA and KSMU, tel. (843) 233-34-78, e mail: pozdeevoskar@rambler.ru2,3

    The article presents the results of a survey of 103 HIV-infected patients. The considered issues are the mycological research of all patients with clinical diagnosis of meningitis and meningoencephalitis. The characteristic is presented of bacterioscopic, strain and immunological methods of research of the clinical material obtained from patients, namely CSF and serum. New data are obtained of the selection pathogenic fungus of Cryptococcus from HIV-infected patients. Frequency of Cryptococcus allocation is associated with age and sex of patients, as well as with the clinical pattern of the disease. The role of cryptococcosis as AIDS-marking disease is proved. The monitoring of the antimycotics sensitivity was held when choosing the Cryptococcus treatment.

    Key words: Сryptococcus, cerebrospinal fluid, serum, HIV-infected, antifungal preparations.

     

     

    REFERENCES

    1. Khostelidi S.N., Sorokina M.M., Borzova Yu.V., Chernopyatova R.M., Bogomolova T.S., Ignat’eva S.M., Frolova E.V., Filippova L.V., Avdeenko Yu.L., Bosak I.A., Tsinzerling V.A., Shurpitskaya O.A., Vasil’eva N.V., Klimko N.N. Pulmonary cryptococcosis in patients without HIV infection. A case report and review of the literature. Problemy meditsinskoy mikologii, 2013, vol. 15, no. 2, pp. 18-24 (in Russ.).

    2. Vasil’eva N.V., Bogomolova T.S., Vybornova I.V., Bosak I.A. Faktory patogennosti Cryptococcus neoformans i ikh rol’ v patogeneze kriptokokkoza [Pathogenicity factors of Cryptococcus neoformans and their role in the pathogenesis of cryptococcosis]. Materialy IX s»ezda Vserossiyskogo nauchno-prakticheskogo obshchestva epidemiologov, mikrobiologov i parazitologov, 2007, vol. 2. P. 221.

    3. Klimko N.N. Mikozy: diagnostika i lechenie, 2-e izdanie [Mycosis: diagnosis and treatment, 2nd edition]. Moscow, 2008. P. 335.

    4. Pokrovskiy V.V. VICh-infektsiya i SPID. Klinicheskie rekomendatsii, 2-e izdanie, pererab. i dop. [HIV infection and AIDS. Clinical practice guidelines, 2nd edition, revised. and ext.]. Moscow: GEOTAR-Media, 2010. 192 p. P. 72.

    5. Zubkov M.N. Sbor, transportirovka biologicheskogo materiala i traktovka rezul’tatov mikrobiologicheskikh issledovaniy. Laboratornaya diagnostika [Collection, transport of biological material and interpretation of the results of microbiological tests. Laboratory diagnosis], 2004, vol. 6, no. 2, pp. 143-154.

    6. Araviyskiy R.A., Klimko N.N., Vasil’eva N.V. Diagnostika mikozov [Diagnosis of fungal infections]. Saint-Petersburg: SPMAPO, 2004. P. 185.

    Метки: antifungal preparations, cerebrospinal fluid, E.N. SHAKHBAZOVA, E.N. ZHAD’KO, E.Yu. KOTLYAR, F.N. NAGIMOVA, HIV-infected, L.N. KILINA, M.P. SHULAYEVA, N.I. GALIULLIN, O.K. POZDEYEV, O.S. ZAKHAROVA, Practical medicine 07 (14) Infectious diseases. Antimicrobial therapy, serum, Сryptococcus

    ‹ Streptococcus Pneumoniae serotypes causing the development of out-of-hospital pneumonia in HIV-infected patients Comparative analysis of the incidence of acute respiratory disease in young patients with chronic bronchitis  ›
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