pm mfvt1
    • Main page
      • About journal
      • Articles. Working with contents
      • Editor-in-chief
      • Editorial Council
      • Editorial Board


      • For authors
      • Standards for formatting information
      • Reviewing
      • Politics editorial board
      • Ethics of journal publications


      • For advertisers
      • Subscription
      • About the Publishing House
      • Contact us
  •  Features of the course of hemorrhagic fever with renal syndrome in children of various ages

    Редактор | 2022, Practical medicine part 20 №7. 2022 | 20 ноября, 2022

    A.KH. BULATOVA1, 2, I.M. KHAERTYNOVA1, V.G. SHAKIROVA1

     1Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan

    2Republic Clinical Infectious Hospital named after Prof. A.F. Agafonov, Kazan

     Contact details:

    Bulatova A.Kh. — post-graduate student of the Department of Infectious Diseases

    Address: 36 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7-909-308-12-51, e-mail: Asiyakhaertynova@gmail.com

    Hemorrhagic fever with renal syndrome (HFRS) is the most common natural focal infection registered in the Republic of Tatarstan. Basically, HFRS affects people of working age, the proportion of children is 2.4%.

    The purpose was to study the clinical features of the HFRS course in children.

    Material and methods. We examined 40 children aged 1 to 17 years with HFRS hospitalized at the Republic Clinical Hospital in 2017–2021. All children were divided into 2 groups according to pubertal age: group 1 consisted of 12 children aged 0 to 8 years, group 2 consisted of 28 children aged 9 to 17 years.

    Results. It was found that children under 8 years were characterized by a milder course of the disease with predominance of infectious-toxic and abdominal syndromes without kidney damage. In children over 8 years old, the disease had a more striking clinical picture, manifesting as infectious-toxic, abdominal syndromes, visual disturbances in the form of foggy vision, kidney damage (decreased diuresis, increased blood creatinine and urea levels), in single cases – effusions into pleural cavity, pericardium, abdominal cavity and pelvic cavity.

    Key words: hemorrhagic fever, epidemic nephropathy, children, puberty.

    REFERENCES

    1. Savitskaya T.A., Ivanova A.V., Isaeva G.Sh. et al. Evaluation of the epidemiological situation of hemorrhagic fever with renal syndrome in the world and Russia, forecast for 2020. Problemy osobo opasnykh infektsiy, 2020, no. 2, pp. 62–70 (in Russ.).
    2. Shakirova V.G., Gayfullina E.G., Khaertynova I.M. Hemorrhagic fever with renal syndrome: analysis of the epidemiological situation in the Republic of Tatarstan for the period 2003–2015.. Dnevnik Kazanskoy meditsinskoy shkoly, 2017, no. 2 (16), pp. 21–24 (in Russ.).
    3. Ivanova A.V., Popova N.V., Karnaukhov I.G., Chumachkova E.A. Hantavirus diseases: a review of the epidemiological situation and epidemiological risks in the regions of the world. Problemy osobo opasnykh infektsiy, 2021, no. 1, pp. 23–31.
    4. Tkachenko E.A., Dzagurova T.K., Bernshteyn A.D. et al. Hemorrhagic fever with renal syndrome (history, problems and perspectives of study). Epidemiologiya i vaktsinoprofilaktika, 2016, no. 3, pp. 23–34 (in Russ.).
    5. Morozov V.G., Ishmukhametov A.A., Dzagurova T.K. et al. Clinical features of hemorrhagic fever with renal syndrome in Russia. Meditsinskiy sovet, 2017, no. 5, pp. 156–161 (in Russ.).
    6. Zhang L., Ma Qs., Zhang Y. et al. Analysis of misdiagnosed cases of hemorrhagic fever with renal syndrome in children: two cases and literature review. BMC Nephrology, 2019, vol. 20 (1), r. 383.
    7. Daviduk, Y.N., Kabwe E., Shakirova V.G. et al. Characterization of the Puumalaorthohantavirus Strains in the Northwestern Region of the Republic of Tatarstan in Relation to the Clinical Manifestations in Hemorrhagic Fever With Renal Syndrome Patients. Frontiers in Pharmacology, 2019, vol. 10, pp. 1–9.
    8. Huttunen N., Mäkelä S., Pokka T. et al. Systematic literature review of symptoms, signs and severity of serologically confirmed nephropathia epidemica in paediatric and adult patients. Scandinavian Journal of Infectious Diseases, 2011, vol. 43 (6–7), pp. 405–410.
    9. Peterkova V.A., Vitebskaya A.V., Geppe N.A. Spravochnik pediatra po detskoy endokrinologii: metodicheskoe posobie [Pediatrician’s Handbook of Pediatric Endocrinology: Methodological Guide]. Moscow: Verdi, 2016. 140 p.
    10. Skorokhodkina, A.A. Vasil’eva R.F. Khakimova R.F. et al. Immunologiya: uchebno-metodicheskoe posobie [Immunology: teaching aid]. Kazan: KGMU, 2017. 117 p.
    11. Joachim R.B., Kobzik L. Why are children more resistant to mortality from severe infections? Future Microbiology, 2018, vol. 13 (14), pp. 1549–1552.
    12. van der Werfften Bosch J., Heyman P., Potters D. et al. Hantavirus Puumala infection as a cause of fever of unknown origin in a child. Acta Paediatr, 2004, vol. 93 (8), rr. 1120–1122.
    13. Steinman J.B., Lum F.M., Ho P.R. et al. Reduced development of COVID-19 in children reveals molecular checkpoints gating pathogenesis illuminating potential therapeutics. Proceedings of the National Academy of Sciences, 2020, vol. 117 (40), rr. 24620–24626.

    Метки: 2022, A.KH. BULATOVA, Children, epidemic nephropathy, hemorrhagic fever, I.M. KHAERTYNOVA, Practical medicine part 20 №7. 2022, puberty, V.G. SHAKIROVA

    ‹ Clinical-laboratory characteristic of hemorrhagic fever with renal syndrome in adults and children  Hysteroscopy pattern of uterine cavity pathology in the late postpartum period ›
    • rus Версия на русском языке


      usa English version site


      Find loupe

      

    • PARTNERS

      пов  logonew
    «Для
    Practical medicine. Scientific and practical reviewed medical journal
    All rights reserved ©