Yu.R. DYMARSKAYA, O.V. LAVROVA

First St. Petersburg State Medical University named after acad. I.P. Pavlov, 6/8 L. Tolstoy St., St. Petersburg, Russian Federation, 197022

Dymarskaya Yu.R. — postgraduate student of the Department of Obstetrics and Gynecology, tel. +7-906-226-52-00, e-mail julia_dym@mail.ru

Lavrova O.V. — D. Med. Sc., leading research associate of the laboratory of genetic mechanisms of lung diseases of the Scientific and Research Institute of Pulmonology, tel. (812) 234-55-09, e-mail: loverova@bk.ru

There was carried out an analysis of the course of pregnancy, delivery and neonatal status in 146 women with bronchial asthma of different severity: 35 — with mild intermittent bronchial asthma; 45 — with mild persistent bronchial asthma; 66 — with moderate to severe bronchial asthma) and 15 pregnant with no allergic and pulmonary diseases (control group). It is shown that the aggravation of asthma is more common in the first half of pregnancy in all groups of patients with persistent bronchial asthma (mild and moderate to severe asthma). There was also found an inverse relationship between the frequency of gestational toxicosis and threatening miscarriage in the 1st trimester of the severity of bronchial asthma. Patients with moderate to severe asthma had a higher incidence of chronic fetal hypoxia, placental insufficiency, as well as the lowest weight of infants, slowing the normalization of the functional state of the newborns, confirmed by Apgar score at 5 min of life. As part of study there were formulated the phenomena of pregnancy and delivery in patients with bronchial asthma of various severity. Prevention, timely diagnosis and treatment of these complications – are the important tasks of practical obstetrics and related disciplines both during outpatient care and hospital care stage.

Key words: pregnancy, bronchial asthma.

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