Evaluation of the risk of antipsychotic-induced metabolic disturbances: possibilities of pharmacogenetic testing
R.F. NASYROVA1, D.V. IVASHCHENKO1, K.K. YAKHIN2, N.G. NEZNANOV1
1St.-Petersburg V.M. Bekhterev Research Psychoneurological Institute, 3 Bekhterev Str., Saint-Petersburg, Russian Federation, 192019
2Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012
Nasyrova R.F. ― D. Med. Sc., Head of the Department of Personalized Psychiatry and Neurology, tel. (812) 670-02-37, e-mail: [email protected]
Ivashchenko D.V. ― resident, tel. (812) 670-02-37, e-mail: [email protected]
Yakhin K.K. ― D. Med. Sc., Professor, Head of the Department of Psychiatry and Narcology, tel. (843) 238-13-88, e-mail: [email protected]
Neznanov N.G. ― D. Med. Sc., Professor, Director, tel. (812) 670-02-37, e-mail: [email protected]
The article discusses the possibility of implementing personalized approaches to the treatment of mental disorders that require the use of antipsychotics. It analyzes the international experience of implementing the results of pharmacogenetic studies in the clinical practice of psychiatric services and the factors limiting the implementation of pharmacogenetic testing in the Russian Federation. The necessity to develop programs of decision-making support is substantiated, which would be available for psychiatrists at their workplaces.
Key words: personalized medicine, pharmacogenetics, antipsychotics, metabolic disturbances.
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