V.D. ZAKHAROV, S.A. BORZENOK, I.M. GORSHKOV, S.V. KOLESNIK, A.I. KOLESNIK, A.V. MIRIDONOVA

Fyodorov Eye Microsurgery Federal State Institution, 59a Beskudnikovsky Blvd., Moscow, Russian Federation, 127486

 Contact:

Zakharov V.D. ― D. Med. Sc., Professor, Head of the Vitreoretinal Surgery Department, tel. (499) 488-85-53, e-mail: info@mntk.ru

Borzenok S.A. ― D. Med. Sc., Professor, Head of the Center for Fundamental and Applied Biomedical Problems, tel. (499) 488-89-93, e-mail: mdborzenok@yandex.ru

Gorshkov I.M. – Cand. Med. Sc., Head of the Department of Vitreoretinal Surgery and Eye Diabetes, tel. (499) 488-84-38, e-mail: soul@rambler.ru

Kolesnik S.V. ― Cand. Med. Sc., Researcher of the Department of Vitreoretinal Surgery and Eye Diabetes, tel. (495) 488-87-17, e-mail: svkolesnik83@gmail.com

Kolesnik A.I. ― Cand. Med. Sc., Researcher of the Department of Vitreoretinal Surgery and Eye Diabetes, tel. (495) 488-89-20 e-mail: doc_ant@mail.ru

Miridonova A.V. ― postgraduate student of the Department of Vitreoretinal Surgery and Eye Diabetes, e-mail: miridonova.anna@mail.ru

 The paper is devoted to the analysis of changes in the vitreo-retinal interface leading to various pathology processes such as epiretinal fibrosis. The epiopathogenetic aspects of forming the idiopathic epiretinal fibrosis are considered, the possible mechanisms of formation and the most significant cell elements involved in the development and progression of the proliferation process.

Key words: vitreoretinal interface, posterior vitreous detachment, epiretinal membrane, extracellular matrix, vitreous cortex, cortical layers

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