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  • Effectiveness of immunoreduction therapy and splenectomy in patients with aplastic anemia by the example of an experience in hematology department of the Republican Clinical Hospital 

    Редактор | 2016, Practical medicine 04 (16) Innovative technologies in medicine. Part 2 | 22 сентября, 2016

    А.V. КОSTERINA1, А.R. AKHMADEEV2, Z.M. NAZIPOVA1, D.I. MARAPOV1

    1Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012

    2Republican Clinical Hospital of the MH of RT, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064

    Коsterina A.V. ― Assistant of the Department of Hospital Therapy, tel. +7-917-273-77-68, e-mail: [email protected]

    Akhmadeev A. R. ― Head of the Department of Hematology, tel. +7-927-240-55-90, e-mail: [email protected]

    Nazipova Z.M. ― student of the 6th course of the Department of general medicine, tel. +7-905-376-21-36, e-mail: [email protected]

    Marapov D.l. ― Assistant of the Department of public health and health care organization, tel. +7-987-288-00-20, e-mail: [email protected] 

    The article presents the results of a study of 16 patients with aplastic anemia in the period of 2012-2015 years who were treated in the Department of Hematology of the Republican Clinical Hospital. There was evaluated the efficacy of immunosuppressive therapy and splenectomy in these patients by statistical analysis of laboratory parameters at the time of admission and discharge. Data were obtained in the study, which has indicated that the results of treatment in two groups of patients have no statistically significant differences. So there is a question to be relevant in the future: whether this category of patients needs splenectomy or not.

    Key words: aplastic anemia, immunosuppressive therapy, splenectomy, results of statistical processing.

     

     

    REFERENCES

    1. Savchenko V.G. Clinical guidelines for the treatment of aplastic anemia. Natsional’noe gematologicheskoe obshchestvo, 2014, pp. 8-22 (in Russ.).
    2. Mamaev N.N. Gematologiya. Rukovodstvo dlya vrachey [Hematology. Guidelines for doctors]. Saint Petersburg: SpetsLit, 2011. No. 2. Pp. 161-177.
    3. Mikhaylova E.A., Savchenko V.G. Splenectomy in programmed therapy of aplastic anemia. Terapevticheskiy arkhiv, 2006, no. 8, pp. 52-57 (in Russ.).
    4. D’yakonov D.A., Pan’kov V.N., Fedorovskaya N.A. et al. Morfometicheskaya estimate prognosis of aplastic anemia in patients after splenectomy. Klinicheskaya praktika, 2014, no. 3, pp. 15-19 (in Russ.).

    Метки: A.V. KOSTERINA, aplastic anemia, D.I. MARAPOV, immunosuppressive therapy, Practical medicine 04 (16) Innovative technologies in medicine. Part 2, results of statistical processing, splenectomy, Z.M. NAZIPOVA, А.R. AKHMADEEV

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