E.A. STEPANOVA¹, O.I. LEBEDEV¹, A.P. KOBZEVA¹, G.M. KOZACHENKO², M.V. POVCHINETS², A.A. ATAMANENKO²

¹Omsk State Medical University, 12 Lenin Str., Omsk, Russian Federation, 644099

²Omsk Clinical Ophthalmological Hospital named after V.P. Vychodtsev, 60 Lermontov Str., Omsk, Russian Federation, 644070

  Stepanova E.A. — Cand. Med. Sc., Assistant of the Ophthalmology Department, e-mail: [email protected]

Lebedev O.I. — D. Med. Sc., Professor, Head of the Ophthalmology Department, e-mail: [email protected]

Kobzeva A.P. — intern of the Ophthalmology Department

Kozachenko G.M. — Head of the Surgery Department

Povchinets M.V. — doctor-ophthalmologist of the Surgery Department

Atamanenko A.A. — doctor-ophthalmologist of the Surgery Department

The paper analyzes different schemes of partial hemophthalmus treatment. A single intravitreal administration of fibrinolytic drug prourokinase proved to be more effective for the hemophthalmos resorption compared to its subconjunctive injections, as a course of 7-10 procedures, as well as compared to treatment with other medications.

Key words: hemophthalmos, intravitreal injection, fibrinolysis.

REFERENCES

1. Volkov V.V., Danilov A.V., Rapis E.G. Gemoftalʹm [Hemophthalmus]. Leningrad: Meditsina, 1990. 62 p.
2. Boyko Eh.V., Danilichev V.F., Sazhin T.G. et al. Methods of clinical application of recombinant prourokinase in ophthalmic practice. Klinicheskaya oftalʹmologiya, 2017, no. 2, pp. 118-129 (in Russ.).
3. Alyabʹeva Zh.Yu., Matveev M.Yu., Evgrafov V.Yu., Domogatskiy S.P. Pharmacokinetics of recombinant prourokinase. Vestn. oftalʹmol, 1998, no. 1, pp. 38-41 (in Russ.).
4. Boyko Eh.V., Danilichev V.F., Sazhin T.G., Martyushin S.V. Experimental study of the pharmacokinetics of recombinant prourokinase by the radionuclide method. Oftalʹmologicheskiy zhurnal, 2003, vol. 394, no. 5, pp. 66-70 (in Russ.).
5. Boyko Eh.V., Danilichev V.F., Sazhin T.G., Aliev Sh.F. Influence of methods of introducing «gemaz» on the effectiveness of treatment of hemophthalmia in diabetic retinopathy. Oftalʹmologicheskie vedomostʹ, 2008, vol. 1, no. 2, pp. 42-47 (in Russ.).
6. Bolkvadze E.R. Gemaza v lechenii vnutriglaznykh travmaticheskikh krovoizliyaniy: avtoref. dis. … kand. med. nauk [Gemase in the treatment of intraocular traumatic hemorrhages. Synopsis of dis. PhD Med. Sciences]. Moscow, 2002. 23 p.
7. Evgrafov V.Yu., Krutenkov O.A., Batmanov Yu.E. Nekotorye podkhody k lecheniyu diabeticheskogo gemoftalʹma [Some approaches to the treatment of diabetic hemophthalmia]. Sovremennye tekhnologii lecheniya vitreoretinalʹnoy patologii: sb. nauch. statey GU MNTK “Mikrokhirurgiya glaza”. Moscow, 2002. No. 4. Pp. 34-37.