M.YU. SMETANIN¹, E.N. LOGINOVA²

 ¹Republican Clinical and Diagnostic Center, Izhevsk

²Omsk State Medical University, Omsk

  Contact details:

Smetanin M.Yu. — PhD (medicine), ultrasound diagnostics doctor of the highest qualification category

Address: 87 Lenin St., Izhevsk, Russian Federation, 426009, tel.: +7 (3412) 37-49-58, e-mail: mail@msmetanin.ru

Cardiac syndromes occupy a special place among the manifestations of undifferentiated connective tissue dysplasia (UCTD), since it is the severity of dysplastic stigmatization of the cardiovascular system (CVS) that determines the individual life and work prognosis in people with UCTD. Predicting adverse cardiovascular events is relevant, in particular, for young women with UCTD, since protecting the health of such patients in a critical demographic situation in the country (low birth rate and high mortality) is one of the most important tasks of modern medicine.

Ultrasound estimation of myocardial deformation indicators in clinical practice provides accurate information about the early stages of cardiovascular diseases (CVD) with a preserved ventricular ejection fraction (EF), which makes it possible to detect early violations of myocardial mechanics and subclinical signs of heart failure (HF).

Key words: connective tissue dysplasia, dysplastic heart, left ventricle myocardial deformation, dysplastic deformation of the left ventricle myocardium.

REFERENCES

1. Gnusaev S.F., Federyakina O.B., Kapustina L.V., Koval’ N.Yu., Borisova S.S., Retunskiy A.V. Tactics of managing children with connective tissue dysplasia of the heart. Rossiyskiy vestnik perinatologii i pediatrii, 2011, no. 6, pp. 41–46 (in Russ.).
2. Smetanin M.Yu., Chernyshova T.E., Pimenov L.T., Kononova N.Yu. Dysplastic heart: is it possible to predict the electrical instability of the myocardium? Meditsinskiy vestnik Severnogo Kavkaza, 2016, no. 2, pp. 353–355 (in Russ.).
3. Kadurina T.I., Gorbunova V.N. Displaziya soedinitel’noy tkani: rukovodstvo dlya vrachey [Connective tissue dysplasia: a guide for physicians]. Saint Petersurg: ELBI-SPb., 2009. P. 702.
4. Zemtsovskiy E.V., Malev E.G., Lobanov M.Yu. Minor anomalies of the heart. Rossiyskiy kardiologicheskiy zhurnal, 2012, no. 93 (1), pp. 77–81 (in Russ.).
5. Vereshchagina G.N. Sistemnye displazii soedinitel’noy tkani. Klinicheskie sindromy, diagnostika, podkhody k lecheniyu: metodicheskoe posobie dlya vrachey [Systemic connective tissue dysplasia. Clinical syndromes, diagnosis, approaches to treatment: a manual for physicians]. Novosibirsk: NGMU, 2008. P. 37.
6. Supranational (international) recommendations for structural anomalies of the heart. Meditsinskiy vestnik Severnogo Kavkaza, 2018, no. 13 (1–2), pp. 272–324 (in Russ.).
7. Trisvetova E.L., Yudina O.A. Anatomiya malykh anomaliy serdtsa [Anatomy of small anomalies of the heart]. Minsk: «Belprint», 2006. P. 104.
8. Nechaeva G.I., Viktorova I.A. Displaziya soedinitel’noy tkani: terminologiya, diagnostika, taktika vedeniya patsientov [Connective tissue dysplasia: terminology, diagnosis, management tactics]. Omsk: BLANKOM, 2007. P. 188.
9. Yakovlev V.M., Nechaeva G.I. Kardio-respiratornye sindromy pri displazii soedinitel’noy tkani [Cardio-respiratory syndromes in connective tissue dysplasia]. Omsk, 1994. P. 217.
10. Druk I.V. Kardiovaskulyarnye sindromy displazii soedinitel’noy tkani: kharakteristika klinicheskikh proyavleniy, prognozirovanie techeniya, metodologiya okazaniya lechebno-profilakticheskoy pomoshchi: dis. … d-ra med. nauk [Cardiovascular syndromes of connective tissue dysplasia: characteristics of clinical manifestations, prognosis of the course, methodology for providing medical and preventive care. Dis. Dr med. sciences]. Omsk. 316 p.
11. Clinical recommendations of the Russian scientific medical society of therapists for the diagnosis, treatment and rehabilitation of patients with connective tissue dysplasia (first revision). Meditsinskiy vestnik Severnogo Kavkaza, 2018, no. 1, 2 (13), pp. 137–210 (in Russ.).
12. Druk I.V., Nechaeva G.I., Lyalyukova E.A., Drokina O.V. Cardiovascular syndromes of connective tissue dysplasia in young people: frequency of registration, formation factors. Lechashchiy vrach, 2014, no. 6, pp. 72–74 (in Russ.).
13. Undifferentiated connective tissue dysplasia (draft clinical guidelines). Terapiya, 2019, no. 7, pp. 9–42 (in Russ.).
14. Druk I.V., Nechaeva G.I., Oseeva O.V. et al. Personalized risk assessment of adverse cardiovascular complications in young patients with connective tissue dysplasia. Kardiologiya, 2015, pp. 3:75–84 (in Russ.).
15. Mor-Avi V., Lang R.M., Badano L.P. et al. Current and evolving Echocardiographic Techniques for the Quantitative Evaluation of Cardiac Mechanics: ASE/EAE Consensus Statement on Methodology and Indications Endorsed by the Japanese Society of Echocardiography. European Journal of Echocardiography, 2011, vol. 12 (3), pp. 167–205. DOI: 10.1093/ejechocard/jer021
16. Ekimova N.A., Katkova L.A., Furman N.V. Evaluation of strain and strain rate of the myocardium by tissue dopplerography (review). Saratovskiy nauchno-meditsinskiy zhurnal, 2013, vol. 9 (1), pp. 50–57 (in Russ.).
17. Pan C., Hoffman R., Kuhl H., Severin E., Franke A., Hanrath P. Tissue tracking allows rapid and accurate visual evaluation of left ventricular function. Eur J Echocardiogr., 2001, vol. 2 (3), pp. 197–202. DOI: 10.1053/euje.2001.0098
18. Stoylen A. Strain rate imaging: Cardiac deformation imaging by ultrasound echocardiography. Tissue Doppler and Speckle tracking, available at: http://folk.ntnu.no/stoylen/strainrate/
19. Tkachenko S.B., Beresten’ N.F. Tkanevoe dopplerovskoe issledovanie miokarda [Tissue Doppler study of the myocardium]. Moscow: Real Taym, 2006. P. 163.
20. Vasyuk Yu.A. Guide to functional diagnostics in cardiology. Modern methods and clinical interpretation. Prakticheskaya meditsina, 2012, p. 164 (in Russ.).
21. Tuaeva Z.R., Kirichenko T.I. Clinical significance of indicators of myocardial deformation in patients with coronary artery disease (literature review). Vestnik novykh meditsinskikh tekhnologiy. Elektronnoe izdanie, 2014, no. 1, p. 164 (in Russ.).
22. Voigt J.U., Exner B., Schmiedehausen R. Strain-Rate Imaging During Dobutamine Stress Echocardiography provides Objective Evidence of Inducible ischemia. Circulation, 2003, vol. 107, pp. 2120–2126.
23. Perk G., Tunick P.A., Kronzon I. Non-Doppler Two-dimensional Strain Imaging by Echocardiography – From Technical Considerations to Clinical Applications. J Am Soc Echocardiogr, 2007, vol. 20 (3), pp. 234–243.
24. Duncan A.E., Alfirevic A., Sessler D.I., Popovic Z.B., Thomas J.D. Perioperative assessment of myocardial deformation. Anesth. Analg, 2014, vol. 118 (3), pp. 525–544. DOI: 10.1213/ANE.0000000000000088
25. Lundback S. Cardiac pumping and function of the ventricular septum. Acta Physiol. Scand. Suppl, 1986, vol. 550, pp. 1–101.
26. Potter E., Marwick Tom H.: Assessment of Left Ventricular Function by Echocardiography. The Case for Routinely Adding Global Longitudinal Strain to Ejection Fraction. JACC Cardiovasc Imaging, 2018, vol. 11 (2), pp. 260–274. DOI: 10.1016/j.jcmg.2017.11.017
27. Lang R.M., Badano L.P., Mor-Avi V. et al. Recommendations for chamber quantification by echocardiography in adults: un update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging, 2015, vol. 16 (3), pp. 233–270.
28. Ponikowski P., Voors A., Anker S.D., Bueno H., Clealand J.G.F., Coats A.J.S. et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur. Heart J, 2016, vol. 37 (27), pp. 2129–2200. DOI: 10.1093/eurheartj/ehw128
29. Drobyazko O.A., Chumakova O.S., Zateyshchikov D.A., Chelombit’ko E.G., Alekhin M.N. Structural and functional features and indicators of deformation of the left ventricle of the heart of athletes according to speckle tracking echocardiography. Sibirskiy zhurnal klinicheskoy i eksperimental’noy meditsiny, 2019, no. 34 (1), pp. 48–53 (in Russ.). DOI: 10.29001/2073-8552-2019-34-1-48-53
30. Marwick Tom H., Abraham T.P. ASE’s Comprehensive Strain Imaging 1st Edition. Elsevier, 2021. P. 256.
31. Abduch M.C., Alencar A.M., Mathias W.Jr., Viera M.L. Cardiac mechanics by speckle tracking echocardiography. Arc Bras Cardiol, 2014, vol. 102 (4), pp. 403–412.
32. Voigt J.U., Pedrizzetti G., Lysyansky P., Marwick T.H., Houle H., Baumann R. et al. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. Eur Heart J Cardiovasc Imaging, 2015, vol. 16, pp. 1–11. DOI: 10.1093/ehjci/jeu184
33. Potapov V.V., Druk I.V., Nechaeva G.I., Smyalovskiy V.E., Kolmenkova I.V., Sidorova N.Yu. Exercise tolerance and speckle tracking characteristics of right ventricular myocardial deformation in young patients with connective tissue dysplasia. Patologiya krovoobrashcheniya i kardiokhirurgiya, 2014, no. 18 (1), pp. 42–46 (in Russ.).
34. Timofeev E.V., Malev E.G., Zemtsovskiy E.V. Myocardial deformation and systolic dysfunction of the left ventricle in hereditary connective tissue disorders. Meditsina: teoriya i praktika, 2021, no. 6 (2), pp. 17–25 (in Russ.).
35. Kalinkina T.V., Lareva N.V., Chistyakova M.V. Modern methods of diagnosing diastolic dysfunction of the left ventricle in patients with essential hypertension. Zabaykal’skiy meditsinskiy vestnik, 2016, no. 2, pp. 115–120 (in Russ.).
36. Zhang H.J., Wang H., Sun T., Lu M.J., Xu N., Wu W.C. et al. Assessment of left ventricular twist mechanics by speckle tracking echocardiography reveals association between LV twist and myocardial fibrosis in patients with hypertrophic cardiomyopathy. Int. J. Cardiovasc. Imaging, 2014, no. 30 (8), pp. 1539–1558. DOI: 10.1007/s10554-014-0509-6
37. Muraru D., Niero A., Rodriguez-Zanella H., Cherata D., Badano L. Three-dimensional speckle-tracking echocardiography: benefits and limitations of integrating myocardial mechanics with three-dimensional imaging. Cardiovasc. Diagn. Ther, 2018, vol. 8 (1), pp. 101–117. DOI: 10.21037/cdt.2017.06.01
38. Park J.H. Two-dimensional Echocardiographic Assessment of Myocardial Strain: Important Echocardiographic Parameter Readily Useful in Clinical Field. Korean Circ. J, 2019, vol. 49 (10), pp. 908–931. DOI: 10.4070/kcj.2019.0200
39. Forsha D., Risum N., Rajagopal S. et al. The Influence of Angle of Insonation and Target Depth on Speckle-Tracking Strain. J Am Soc Echocardiogr, 2015, vol. 28 (5), pp. 580–586. DOI: 10/1016/j.echo.2014.12.015
40. Faletra F.F., Ramamurthi A., Dequarti M.C. et al. Artifacts in Three-dimensional Trans esophageal Echocardiography. J Am Soc Echocardiogr, 2014, vol. 27 (5), pp. 453–462. DOI: 10.1016/j.echo.2014.02.003