A.E. APRELEV¹, Yu.A. BARBOS^2,3, I.Zh. MUKHANKO⁴, N.L. CHEREDNICHENKO², Z.F. ABDULGAZIZOVA⁵, V.V. SUMENKO¹

 ¹Orenburg State Medical University of the Ministry of Healthcare of the Russian Federation, 6 Sovetskaya Str., Orenburg, Russian Federation 460000

²Stavropol State Medical University of the Ministry of Healthcare of the Russian Federation, 310 Mira Str., Stavropol, Russian Federation, 355017

³Stavropol Regional Clinical Hospital, 1 Semashko Str., Stavropol, Russian Federation, 355030

⁴Mineralnye Vody District Hospital, 67A Gagarina Str., Mineralnye Vody, Russian Federation, 357202

⁵Orenburg Regional Clinical Hospital, 23 Aksakova Str., Orenburg, Russian Federation, 460018

 Aprelev A.E. ― D. Sc. (medicine), Associate Professor, Head of the Department of Ophthalmology, tel. (3532) 31-52-11, e-mail: [email protected]

Barbos Yu.A. ― extramural post-graduate student of the Department of Ophthalmology with a course of additional professional education, Doctor at the Division of Ophthalmology, e-mail: [email protected]

Mukhanko I.Zh. – Chief Visiting Ophthalmologist of the city of Mineralnye Vody, e-mail: [email protected]

Cherednichenko N.L. – PhD (medicine), Associate Professor, Head of the Department of Ophthalmology with a course of additional professional education, tel. (8652) 56-66-89, e-mail: [email protected]

Abdulgazizova Z.F. – Head of the Division of Ophthalmology No.2, e-mail: [email protected]

Sumenko V.V. – PhD (medicine), Associate Professor of the Department of Pediatrics at Institute of Vocational Education, e-mail: [email protected]

The article presents data of a multicenter study of effectiveness of neuroprotective treatment and its effect on the quality of life of patients with primary open-angle glaucoma (POAG). Evaluation of dynamics of visual acuity, intraocular pressure, summary fields of vision, photostress test, contrast sensitivity and quality of life (according to the NEIVFQ-25 questionnaire) in patients with traditional neuroprotective therapy of glaucoma and with the additional application of Retinalamin, is made. Data on the improvement of visual functions in patients who have received treatment with the test drug were obtained. Improving the quality of life with a single course of Retinalamin (intramuscular) was established in patients with POAG at all stages (I-III). In the group with traditional neuroprotective treatment, an improvement in the quality of life (p <0.05) at the end of the study was noted only in patients in II B and C subgroups.

Key words: glaucoma, quality of life, questionnaire NEIVFQ-25, photostress test, Retinalamin, neuroprotection, contrast sensitivity.

(For citation: Aprelev A.E., Barbos Yu.A., Mukhanko I.Zh., Cherednichenko N.L., Abdulgazizova Z.F., Sumenko V.V. Dynamics of functional indicators of the visual organ and quality of life of patients with glaucoma against the background of neuroprotective treatment. Practical Medicine. 2018)

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