Distinctive features of the results of operative treatment of intraarticular and extraarticular fractures in HIV-infected patients
S.N. KHOROSHKOV1,2, N.G. DORONIN1, 2, N.V. YARIGIN2, V.G. BOSYKH2, A.M. CHARCHYAN1, M.V. NAUMENKO1
1City Clinical Hospital named after F.I. Inosemtsev, Moscow
2A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow
Contact details:
Khoroshkov S.N. — MD, Professor of the Department of Traumatology and Orthopedics
Address: 20 Delegatskaya St., building 1, Moscow, Russian Federation, 127473, tel.: +7-916-181-47-73, e-mail: Khoroshkov@yandex.ru
The purpose — to evaluate the effectiveness of the developed algorithm for determining the tactics and methods of treating intra-articular fractures in HIV-infected patients.
Material and methods. From 2016 to 2020, 56 HIV-infected patients with intra-articular fractures underwent surgical treatment. In the course of treatment, an algorithm developed in the clinic for determining the tactics and method of treating HIV-infected patients was used, which proved effective in treating extra-articular fractures.
Results. The results were evaluated in the average expected time of the fracture consolidation of the selected location, as well as 6 and 12 months from the moment of surgery using the algorithm developed by us for determining the tactics and method of treating fractures in HIV-infected patients. Good results (according to the Luboschitz — Mattis scale) were noted in 16 (30,8%), satisfactory — in 27 (51,9%) and unsatisfactory — in 9 (17,3%) cases. For patients of this category, the most typical complications were the rapid progression of deforming arthrosis of the joints, the secondary displacement of bone fragments against the background of bone resorption, and the development of an inflammatory process of predominantly non-infectious etiology.
Conclusion. The use of the developed algorithm for determining the tactics and method of treatment in HIV-infected patients with extra-articular fractures, taking into account the effect of HIV infection and antiretroviral therapy on the processes of bone remodeling and soft tissue regeneration, can significantly reduce the number of unsatisfactory treatment results. At the same time, the peculiarities of the effect of HIV infection on the state of cartilage, subchondral bone and synovial fluid determine the nature and risks of postoperative complications in HIV-infected patients. In the future, it is planned to correct the developed algorithm taking into account the data obtained and to carry out a comparative analysis of the treatment results.
Key words: HIV, fracture, osteosynthesis, complications.
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