Difficulties of clinical diagnosis of Conn’s syndrome (on the 65th anniversary of description)
S.N. IVANOVA1, 2 , O.A. SHORINA1, YU.E. SCHKERSKIYI2, N.A. SCHKERSKAYA2
1 Northern State Medical University, Arkhangelsk
2 Arkhangelsk Regional Clinical Hospital, Arkhangelsk
Contact details:
Ivanova S.N. — Ph. D. (medicine), Associate Professor of the Department of Hospital Therapy end Endocrinology, therapist
Address: 51 Troitsky prospekt, Russian Federation, Arkhangelsk, 163000, tel.: +7 (8182) 632-996, e-mail: [email protected]
The purpose — to present data on diagnosting the primary hyperaldosteronism due to an adrenal tumor, first described by Jerome Conn in November 1955.
Material and methods. Conn’s syndrome includes arterial hypertension, muscle paralysis, and renal manifestations against the background of hypokalemia. A description of two clinical observations with different debuts of primary hyperaldosteronism (potassium penic kidney and hypokalemic paralysis) is presented. Timely diagnosis and operative treatment to remove an adrenal tumor in patients allowed stopping the disease clinical manifestations.
Conclusion. The article is of interest to practitioners, as Conn’s syndrome debuted with hemorrhagic stroke and myasthenia gravis in combination with arterial hypertension and hypokalemia.
Key words: primary hyperaldosteronism, Conn’s syndrome, aldosteroma, arterial hypertension, hypokalemia, potassium penic kidney, hypokalemic paralysis.
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