A.G. KHARITONOV¹, O.B. SHCHUKINA¹, V.Y. SOBKO² 

¹Northen-West state medical university named after I.I. Mechnikov, Kirochnaya street, 41, Saint-Petersburg, Russian Federation, 191015

²Consultative and diagnostic centre with polyclinic, Morskoy prospect, 3, Saint-Petersburg, Russian Federation, 197110

Kharitonov Andrey — assistant of the department of gastroenterology and dietology, ph. (812) 235-10-93, e-mail: [email protected]¹

Shchukina Oksana — PhD, docent of the department of gastroenterology and dietology, ph. (812) 235-10-93; e-mail: [email protected]¹

Sobko Victor — radiologist, ph. (812) 325-00-03, e-mail: [email protected]²

This article presents a clinical case of patient with Crohn’s disease of small bowel localization. The complexity of diagnosis was due not only to the localization of disease, but also comorbidities. Authors review current approaches of visualization of small intestine and screening for celiac disease in daily practice.

Key words: Crohn’s disease, small bowel, MRI-enterography, celiac disease.

REFERENCES

1. Heresbach D., Alexandre J.L., Branger B., Bretagne J.F. et al. Frequency and significance of granulomas in a cohort of incident cases of Crohn’s disease. Gut, 2005, vol. 54, no. 2, pp. 215-222.

2. Magro F., Langner C., Driessen A., Ensari A. et al. European consensus on the histopathology of inflammatory bowel disease. J. Crohns Colitis, 2013, vol. 7, no. 10, pp. 827-851.

3. Husby S., Koletzko S., Korponay-Szabo I.R. et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease. JPGN, 2012, vol. 54, no. 1, pp. 136-160.

4. Salmi T.T., Collin P., Korponay-Szabo I.R. et al. Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits. Gut, 2006, vol. 55, pp. 1746-1753.

5. Adler G. Bolezn’ Krona i yazvennyy kolit [Crohn’s disease and ulcerative colitis]. Moscow: GEOTAR-MED, 2001. 500 p.

6. Alekseeva O.P., Kolodey E.N., Mironov N.N. Dynamics of the clinical course , diagnosis and treatment of inflammatory bowel disease in the Nizhny Novgorod region in the period 2005-2010. Meditsinskiy al’manakh, 2013, vol. 25, no. 1, pp. 71-73 (in Russ.).

7. Bodryagina E.S., Abdulganieva D.I., Odintsova A.Kh. Clinical and epidemiological indicators of inflammatory bowel disease in the Republic of Tatarstan. Lechashchiy vrach, 2013, no. 7, pp. 21-26 (in Russ.).

8. Dignass A., Assche G., Lindsay J.O. et al. The Second European evidence-based consensus on the diagnosis and management of Crohn’s disease: Current management. J. Crohns Colitis, 2010, vol. 4, pp. 28-62.