D.S. SARKSYAN¹, O.V. MALININ¹, M.V. DUDAREV¹, L.I. KHALITOVA¹, V.G. IVANOV¹, G.M. IVANOVA¹^—², N.I. BULATOVA² 

¹Izhevsk State Medical Academy, 281 Communarov St., Izhevsk, Russian Federation, 426000

²2^nd Republican Clinical Hospital 230 Svobody St., Izhevsk, Russian Federation, 426000

Sarksyan D.S. — Cand. Med. Sc., Associate Professor of the Department of Infectious Diseases and Epidemiology, tel. +7-904-310-64-14, e-mail: [email protected]¹

Malinin O.V. — Cand. Med. Sc., Associate Professor, Head of the Department of Infectious Diseases and Epidemiology, tel. +7-912-762-90-89, e-mail: [email protected]¹

Dudarev M.V. — D. Med. Sc., Associate Professor, Head of the Department of Outpatient Therapy, tel. +7-912-767-28-33, e-mail: [email protected]¹

Khalitova L.I. — postgraduate student of the Department of Outpatient Therapy, tel. +7-912-455-84-60, e-mail: [email protected]¹

Ivanov V.G. — Cand. Med. Sc., Associate Professor of the Department of Clinical Biochemistry, tel+7-906-819-88-08, e-mail: [email protected]¹

Ivanova G.G. — Cand. Med. Sc., Assistant Lecturer of the Department of Clinical Biochemistry, tel. +7-906-819-88-08, e-mail: [email protected]^1,2

Bulatova N.I. — laboratory doctor, tel. (3412) 78-37-43²

The content of cystatin C in serum in Ixodidea tick borreliosis caused B. miyamotoi was studied. To confirm the specific diagnosis, PCR technique was used. The patients were divided into 2 groups by the presence of clinical-laboratory signs of renal pathology. For each group a number of indicators were evaluated characterizing the filtration and concentration functions of kidney. The correlation of these parameters with the content of cystatin C serum was studied. It was shown that serum cystatin C is a more sensitive marker of glomerular dysfunction than urea and creatinine levels in a single study.

Key words: Ixodidea tick borreliosis, Borrelia miyamotoi, clinical pattern, renal lesions, serum cystatin C.

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