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  •  Diagnosing hyperbilirubinemia in young children

    Редактор | 2022, Original articles, Practical medicine part 20 №2. 2022 | 5 апреля, 2022

    O.V. KISELNIKOVA1, L.I. MOZZHUKHINA1, E.A. PANOVA2, V.F. TEYF2, E.A. KISELNIKOVA1, A.A. SNIGIREV1

     1Yaroslavl State Medical University, Yaroslavl

    2Regional Children’s Clinical Hospital, Yaroslavl

     Contact details:

    Kiselnikova O.V. — PhD (medicine), Associate Professor of the Pediatrics Department

    Address: 5 Revolyutsionnaya St., Yaroslavl, tel.: +7-910-975-00-04, e-mail: kiselnikova1@yandex.ru

    One of the early manifestations of a wide range of the hepatobiliary system diseases in pediatric practice is hyperbilirubinemia syndrome. The greatest concern is caused by conditions accompanied by «direct» hyperbilirubinemia, in which the level of conjugated bilirubin is more than 15% of the total level. Such hyperbilirubinemia is commonly called «cholestatic». Cholestatic liver diseases are very diverse, while underestimation of the pathological process dynamics and delayed therapeutic intervention can lead to death or severe disability. The article presents the clinical and anamnestic features of newborns and young children with the syndrome of «direct» hyperbilirubinemia to optimize the diagnosis and tactics of management, and a clinical case of late diagnosis of biliary atresia with a hyperbilirubinemia syndrome.

    Key words: young children, conjugated hyperbilirubinemia, cholestasis, biliary atresia, gamma-glutamyl transpeptidase.

     REFERENCES

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    Метки: 2022, A.A. SNIGIREV, biliary atresia, cholestasis, conjugated hyperbilirubinemia, E.A. KISELNIKOVA, E.A. PANOVA, gamma-glutamyl transpeptidase, L.I. MOZZHUKHINA, O.V. KISELNIKOVA, Practical medicine part 20 №2. 2022, V.F. TEYF, young children

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