D.R. AKBEROVA¹, E.S. BODRYAGINA¹, L.I. MINGATINA²

 ¹Kazan State Medical University, Kazan

²Republican Clinical Hospital, Kazan

Contact details:

Akberova D.R. — PhD (Medicine), Assistant Lecturer of the Department of Hospital Therapy

Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7 (843) 237-32-61, e-mail: dile4ek@mail.ru

The article presents data on the combination of dermatological changes and lesions of the gastrointestinal tract. Some gastroenterological diseases can manifest themselves with skin lesions, among other things. In some cases, skin changes may precede symptoms of diseases of the digestive tract. Various skin lesions can occur in diseases of the upper gastrointestinal tract, malabsorption syndrome, inflammatory bowel diseases, celiac disease, and may also be manifestations of deficiency and hereditary conditions and syndromes.

Key words: skin lesions, dermatology, gastrointestinal tract.

REFERENCES

1. Uspenskaya Yu.B. Chronic skin diseases through the prism of gastrointestinal tract pathology. Effektivnaya farmakoterapiya, 2016, vol. 30, pp. 34–36 (in Russ.).
2. Matushevskaya E.V., Komissarenko I.A. Skin manifestations of gastrointestinal tract diseases. Eksperimental’naya i klinicheskaya gastroenterologiya, 2019, no. 6 (166), pp. 86–92 (in Russ.).
3. Skuhala T. et al. Analysis of types of skin lesions and diseases in everyday infectious disease practice — how experienced are we? Life, 2022, vol. 12 (7), p. 978.
4. Klinicheskie rekomendatsii. Bronkhial’naya astma [Clinical guidelines. Bronchial asthma], 2021.
5. Goel V., Sil A., Das A. Cutaneous manifestations of chronic kidney disease, dialysis and post-renal transplant: A review. Ind. J. Dermatol, 2021, vol. 66 (1), pp. 3–11.
6. Rahvar M., Kerstetter J. Cutaneous manifestation of gastrointestinal disease. J. Gastroint. Oncol, 2016, vol. 7 (1), p. S44.
7. Brenner E.J., Long M.D. Diagnosis and treatment of dermatologic diseases in inflammatory bowel disease. Curr. Opin. Gastroenterol, 2019, vol. 35 (4), pp. 330–336.
8. Lu C.Y. et al. Gastrointestinal involvement of primary skin diseases. J. Eur. Acad. Dermatol. Venereol, 2020, vol. 34 (12), pp. 2766–2774.
9. Dolgushina A.I. et al. Esophageal lichen planus as a cause of dysphagia: a literature review and clinical observation. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii, 2023, vol. 33, no. 4, pp. 76–84 (in Russ.).
10. Guarneri C. Et al. Helicobacter pylori and skin diseases: a comprehensive review of the available literature. Eur. Rev. Med. Pharmacol. Sci, 2020, vol. 24 (23).
11. Yu M. et al. Helicobacter pylori infection and psoriasis: a systematic review and meta-analysis. Medicina, 2019, vol. 55 (10), p. 645.
12. Zheleznov S. et al. Gastritis can cause and trigger chronic spontaneous urticaria independent of the presence of Helicobacter pylori. Int. Arch. Allergy Immunol, 2018, vol. 175 (4), pp. 246–251.
13. Ivashkin V.T. et al. Clinical guidelines of the Russian Gastroenterological Association and the RENDO Endoscopic Society for the diagnosis and treatment of gastritis and duodenitis. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii, 2021, vol. 31, no. 4, pp. 70–99 (in Russ.).
14. Zaslavskiy D.V. et al. Porazheniya kozhi pri boleznyakh vnutrennikh organov [Skin lesions in diseases of internal organs], 2020.
15. DiBaise M., Tarleton S.M. Hair, nails, and skin: differentiating cutaneous manifestations of micronutrient deficiency. Nutr. Clin. Practice, 2019, vol. 34 (4), pp. 490–503.
16. National Institutes of Health et al. Office of Dietary Supplements. Vitamin E: fact sheet for health professionals. March 26, 2021.
17. Lazebnik L.B. et al. Recommendations for the diagnosis and treatment of celiac disease in adults. Eksperimental’naya i klinicheskaya gastroenterologiya, 2015, no. 5 (117), pp. 3–12 (in Russ.).
18. Abenavoli L. et al. The skin in celiac disease patients: the other side of the coin. Medicina, 2019, vol. 55 (9), p. 578.
19. Aleksandrov T.L. et al. Skin diseases and inflammatory bowel diseases. Literature review. Meditsinskiy sovet, 2020, no. 5, pp. 108–113 (in Russ.).
20. Tarasova L.V. et al. Management of patients with inflammatory bowel diseases and extraintestinal skin manifestations. Eksperimental’naya i klinicheskaya gastroenterologiya, 2022, no. 11 (207), pp. 252–258 (in Russ.).
21. Shelygin Yu.A. et al. Klinicheskie rekomendatsii Yazvennyy kolit (K51), vzroslye [Clinical guidelines Ulcerative colitis (K51), adults], 2023.
22. Valitova A.D., Galieva A.M., Mukhametova D.D. et. al. Manifestation of extraintestinal manifestations of ulcerative colitis after colectomy. Terapiya, 2024, vol. 10, no. 3, pp. 110–114 (in Russ.). DOI: 10.18565/therapy.2024.3.110-114
23. Deckers I.E., Benhadou F., Koldijk M.J. et al. Inflammatory bowel disease is associated with hidradenitis suppurativa: results from a multicenter cross- sectional study. J. Am. Acad. Dermatol., 2017, vol. 76, pp. 49–53.
24. Brenner E.J., Long M.D. Diagnosis and treatment of dermatologic diseases in inflammatory bowel disease. Curr. Opin. Gastroenterol, 2019, vol. 35 (4), pp. 330–336.
25. De Francesco M.A., Caruso A. The gut microbiome in psoriasis and crohn’s disease: Is its perturbation a common denominator for their pathogenesis? Vaccines, 2022, vol. 10 (2), p. 244.
26. Armstrong A.W., Read C. Pathophysiology, Clinical Presentation, and Treatment of Psoriasis: A Review. JAMA, 2020, vol. 323 (19), pp. 1945–1960.
27. Wang W.M., Jin H.Z. Biologics in the treatment of pustular psoriasis. Exp. Opin. Drug Safety, 2020, vol. 19 (8), pp. 969–980.