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  • Clinical significance of hepcidin in case of community-acquired pneumonia complicated with anemia

    Редакция | 2014, Articles based on dissertstions, Practical medicine 03 (14) Modern questions of diagnostics | 15 июля, 2014

    Yu.E. NIKITIN, E.N. NIKITIN, A.E. SHKLYAEV

    Izhevsk State Medical Academy, 281 Kommunarov St., Izhevsk, Russian Federation 426034

    Nikitin Yu.E.— postgraduate student of the Department of Intermediate Level Therapy with the Courses of Endocrinology and Hematology, tel. (3412) 46-55-78, е-mail: juranikitin@mail.ru

    Nikitin E.N. — D. Med. Sc., Professor of the Department of Intermediate Level Therapy with the Courses of Endocrinology and Hematology, tel. (3412) 46-85-36, е-mail: nikitinen@list.ru

    Shklyaev A.E. — D. Med. Sc., Professor of the Department of Intermediate Level Therapy with the Courses of Endocrinology and Hematology, tel. (3412) 46-55-78, e-mail: shklyaevaleksey@gmail.com

    This article reports the results of determining the peptide hormone hepcidin in 64 patients with community-acquired pneumonia. The interaction between hepcidin and interleukine-6, —10, erythropoietin, indicators of iron metabolism and peripheral blood is explained. Is presented the role of hepcidin in pathogenesis of anemia in case of community-acquired pneumonia. New data were found concerning the influence of hepcidin on recovery of iron metabolism and level of hemoglobin on outcomes of community-acquired pneumonia.

    Key words: community-acquired pneumonia, anemia, hepcidin, cytokines, iron metabolism.

     

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    Метки: A.E. SHKLYAEV, anemia, community-acquired pneumonia, cytokines, E.N. NIKITIN, hepcidin, iron metabolism, Practical medicine 03 (14) Modern questions of diagnostics, Yu.E. NIKITIN

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