G.R. ABRAMYAN

Republican Institute of Reproductive Health, Perinatology, Obstetrics and Gynecology of Armenia, 6/2 Markaryan Str., Yerevan, Armenia, 0078

Moscow First Medical University named after I.M. Sechenov, 2 Bolshaya Pirogovskaya Str., Moscow, Russian Federation, 119991

Abramyan G.R. — Cand. Med. Sc., Associate Professor of the Department of Obstetrics and Gynecology No. 2, tel. (37410) 34-18-83, e-mail: [email protected]

With vast clinical material, the author substantiates the significance of pro-angiogenic and anti-angiogenic factors (PIGF and sFlt-1), as well as ratio of the latter, for prognosis of preeclampsia development (increase of ratio of sFlt-1 level to PlGF level), and, consequently, prognosis of the course and outcome of pregnancy. Also, analysis was carried out of the abovementioned factors in groups with spontaneous and “assisted” (after in vitro fertilization) pregnancies. The important role of these factors for IVF results forecasting was stated.

Key words: placental growth factor (PIGF), soluble variation of fms-like tyrosine kinase (sFlt-1), PIGF/sFlt-1, preeclampsia, in vitro fertilization (IVF).

References

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