D.D. MUKHAMETOVA¹, Е.S. BODRYAGINA¹, А.V. GORN¹, А.D. KHUSAINOVA¹, D.I. ABDULGANIEVA^1, 2, A.KH. ODINTSOVA², L.R. SADYKOVA², N.A. CHEREMINA²

 ¹Kazan State Medical University, Kazan

²Republic Clinical Hospital, Kazan

 Contact details:

Mukhametova D.D. — PhD (medicine), Assistant Lecturer of the Department of Hospital Therapy

Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7 (843) 237-32-61, e-mail: dilyara.muhametova@kazangmu.ru

 The paper presents the results of a survey of 35 patients with liver diseases of various etiologies hospitalized in Gastroenterology Department of Republic Clinical Hospital in Kazan. The patients were distributed according to etiology: liver cirrhosis — 28 (80%), acute hepatitis — 5 (14.3%), after liver transplantation — 2 (5.7%). The patients underwent a complete clinical examination, and psychometric tests were additionally used to assess the stage of hepatic encephalopathy. Blood ammonium level was determined in all patients using the PocketChem BA PA-4140 blood ammonia meter. Connect-the-Numbers Test revealed encephalopathy in 97.1% of patients with liver diseases, while latent hepatic encephalopathy was observed in 47% cases. According to the West-Haven criteria, hepatic encephalopathy was diagnosed in 80% patients. Hyperammonemia was determined in 80% of patients with liver diseases. There was some relationship between the ammonium level and the stage of hepatic encephalopathy.

Key words: liver cirrhosis, hepatic encephalopathy, hyperammonemia, hepatitis.

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