V.V. TUZLAEV¹, V.V. EGOROV^1,2, I.Z. KRAVCHENKO¹, G.P. SMOLYAKOVA^1,2

¹Khabarovsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 211 Tikhookeanskaya Str., Khabarovsk, Russian Federation, 680033

²Postgraduate Institute for Public Health Workers, 9 Krasnodarskaya Str., Khabarovsk, Russian Federation, 680000

 Tuzlaev V.V. ― ophthalmologist of the Laser Surgery Department, tel. (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru, ORСID ID: 0000-0003-1601-9294

Egorov V.V. ― D. Sc. (medicine), Professor, Director, Head of the Ophthalmology Department, tel. (4212) 22-51-21, e-mail: naukakhvmntk@mail.ru, ORСID ID: 0000-0002-9888-7353

Kravchenko I.Z. ― Head of the Laser Surgery Department, tel. (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru, ORСID ID: 0000-0003-4715-4130

Smoliakova G.P. ― D. Sc. (medicine), Professor, ophthalmologist of the Clinical-Expertise Department, Professor of the Ophthalmology Department, tel. (4212) 22-51-21, e-mail: naukakhvmntk@mail.ru, ORСID ID: 0000-0002-6943-5518

 The objective was to study the structure and frequency of clinical manifestations of ocular ischemic syndrome in stenosing internal carotid artery (ICA) diseases and to analyze the background causes of their occurrence.

Material and methods. The study included 60 patients (34 men, 26 women) with ocular ischemic syndrome (OIS), who were observed at S. Fedorov Eye Microsurgery Institution and Federal Center for Cardiovascular Surgery in Khabarovsk.

All patients underwent standard and specialized ophthalmological examination. Assessment of blood flow in brachiocephalic vessels was performed by ultrasound scanning and spiral computed tomography.

Results. Among the examined patients with OIS, intermediate degree of stenosis of the ICA predominated ― 68.3% of cases, expressed degree of stenosis was significantly less frequent ― 23.4%, and small stenosis ― 8.3% of cases. The primary chronic type prevailed and amounted to 66.7%. According to the frequency of occurrence, the largest specific weight is occupied by ischemic optic neuro-opticopathy, both in acute and chronic type.

Conclusions. OIS is a multifactorial disease that requires a multidisciplinary approach of narrow specialists, timely diagnosis and treatment to preserve the vision and quality of life of patients.

Key words: ocular ischemic syndrome, internal carotid artery, stenosis.

(For citation: Tuzlaev V.V., Egorov V.V., Kravchenko I.Z., Smoliakova G.P. Clinical features of ocular ischemic syndrome in atherosclerotic lesions of the internal carotid artery. Practical Medicine. 2018)

REFERENCES

1. Zavgorodnyaya T.S., Sarzhevskaya L.E., Bezdenezhnaya O.A., Bezugla E.A. Glaznoy ishemicheskiy sindrom. Sovremennye printsipy diagnostiki i lecheniya [Ocular ischemic syndrome. Modern principles of diagnosis and treatment]. Zaporozh’e, 2012. 248 p.
2. Tarasova L.N. Glaznoy ishemicheskiy sindrom [Ocular ischemic syndrome]. Moscow: Meditsina, 2003. 176 p.
3. Bondar’ V.Yu., Maslov M.G., Netbay N.N. et al. Features of the clinical course of the hospital period after carotid stenting and carotid endarterectomy. Angiologiya i sosudistaya khirurgiya, 2014, vol. 20, no. 2, p. 56 (in Russ.).
4. Gavrilenko A.V., Kuklin A.V., Abramyan A.V., Kiseleva T.N. Results of carotid endarterectomy in patients with ocular ischemic syndrome caused by carotid stenosis. Annaly khirurgii, 2014, no. 1, pp. 30-37 (in Russ.).
5. Kiseleva T.N., Kravchuk E.A. Osobennosti glaznogo i tserebral’nogo krovotoka pri atrofii zritel’nogo nerva [Features of the eye and cerebral blood flow in atrophy of the optic nerve]. Materialy VIII Vserossiyskoy nauchno-praktich. konf. s mezhdunarodnym uchastiem “Fedorovskie chteniya”. Moscow, 2009. Pp. 100-103.
6. Makkaeva S.M. Osobennosti glaznogo ishemicheskogo sindroma pri distsirkulyatornoy entsefalopatii: avtoref. dis. … dokt. med. nauk [Features of ocular ischemic syndrome with dyscirculatory encephalopathy. Synopsis of dis. Dr med. sciences]. Moscow, 2010. 53 p.
7. Tuzlaev V.V., Egorov V.V., Kravchenko I.Z. et al. Results of combined treatment of chronic ischemic retinopathy in patients with atherosclerotic stenosis of the internal carotid artery. Sovremennye tekhnologii v oftal’mologii, 2018, no. 4 (24), pp. 242-246 (in Russ.).
8. Chen C.S., Miller N.R. Ocular ischemic syndrome: review of clinical presentations, etiology, investigation, and management. Compr. Ophthalmol. Update, 2007, vol. 8 (1), pp. 17-28.
9. Vlasov S.K. Changes in the organ of vision in pathological tortuosity and stenotic atherosclerosis of the carotid arteries. Vestnik oftal’mologii, 2010, no. 5, pp. 58-62 (in Russ.).
10. Sivalingam A., Brown G.C., Magargal L.E. The ocular ischemic syndrome. III. Visual prognosis and the effect of treatment. International Ophthalmology, 1991, vol. 15, issue 1, pp. 15-20.
11. Makhkamova D.K. Etiopathogenesis of ocular ischemic syndrome. Vestnik oftal’mologii, 2017, vol. 133, no. 2, pp. 120-124 (in Russ.).
12. Katsnel’son L.A., Forofonova T.I., Bunin A.Ya Sosudistye zabolevaniya glaz [Vascular diseases of the eye]. Moscow: Meditsina, 1990. 240 p.
13. Omarzhanova I.I. Effektivnost’ rekonstruktivnykh operatsiy na sonnykh arteriyakh u bol’nykh s glaznym ishemicheskim sindromom, obuslovlennym patologicheskoy izvitost’yu vnutrenney sonnoy arterii: avtoref. dis. … kand. med. nauk [The effectiveness of reconstructive operations on the carotid arteries in patients with ocular ischemic syndrome due to the pathological tortuosity of the internal carotid artery. Synopsis of dis. PhD med. sciences], 2013.
14. Kaetkina E.V., Chistyakova S.V., Kuvyrkova O.I. Results of complex treatment of ocular ischemic syndrome. Vestnik Orenburgskogo gosudarstvennogo universiteta, 2015, no. 12 (187), pp. 100-103 (in Russ.).
15. Makhkamova D.K. Magnetic resonance tractography as a method of choice for neuroimaging in ocular ischemic syndrome. Sovremennye tekhnologii v oftal’mologii, 2016, no. 3, pp. 82-85 (in Russ.).
16. Borisova L.I., Cherednichenko L.P., Karpov S.M. Ophthalmologic manifestations of osteochondrosis of the cervical spine depending on the stage of the pathological process. Fundamental’nye issledovaniya, 2014, no. 4-1, pp. 40-43 (in Russ.).
17. Terelak-Borys B., Skonieczna K., Grabska-Liberek I. Ocular ischemic syndrome ― a systematic review. Med. Sci. Monit, 2012, vol. 18, no. 8, pp. 138-144.