K.A. CHEREDNIKOVA, N.YU. FILINA, N.V. BOLOTOVA, M.G. PETROVA

 Saratov State Medical University named after V.I. Razumovsky, Saratov

 Contact details:

Cherednikova K.A. — PhD (medicine), Assistant Professor of the Department of Propaedeutics of Children’s Diseases, Pediatric Endocrinology and Diabetology

Address: 137 Bolshaya Sadovaya St., Saratov, Russian Federation, 410054, tel.: +7-927-147-77-86, e-mail: iw.nazarenko2012@yandex.ru

 The purpose — to evaluate the metabolic status of patients with constitutional growth and puberty retardation in comparison with healthy peers.

Material and methods. The study included 100 teenage boys aged 15 y. o.: the main group (n = 70) — patients with constitutional growth and puberty retardation, the comparison group (n = 30) — healthy adolescents. The indicators of the metabolic status of adolescents were evaluated clinically and by laboratory indices. It was shown that patients with CGPR with androgen deficiency have significant deviations in the metabolic status, manifested by a negative nitrogen balance, dyslipidemia, and the formation of presarcopenic syndrome.

Key words: growth retardation, delayed puberty, testosterone, bioimpedansometry.

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