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  • Clinical and epidemiological features, diagnosis and treatment of toxocariasis in children

    Редактор | 2019, Original articles, Practical medicine part 17 №8. 2019 | 28 ноября, 2019

    F.S. GILMULLINA

    Kazan State Medical University of the Ministry of Healthcare of the Russian Federation, Kazan

    Contact:

    Gilmullina F.S. — PhD (medicine), Associate Professor of the Department of Infectious Diseases

    Address: 49 Butlerov Str., Kazan, Russian Federation, 420012, tel. +7-917-897-53-68, e-mail: [email protected]

    The purpose of the study is to study the clinical, epidemiological, laboratory features and effectiveness of treatment of toxocariasis in children.

    Material and methods. 33 children undergoing clinical examination diagnosed with toxocariasis, confirmed by detection of antibodies to toxocaras in titers ≥ 1:800 by enzyme-linked immunosorbent assay.

    Results and conclusion. It was revealed that 75.8% of children with toxocariasis live in homes with household plots, 72.7% of children have prolonged contact with pets (cats, dogs), 48.5% suffer from geophagy. The predominant clinical manifestations of the visceral form of toxocariasis are bronchopulmonary (39.4%) and abdominal syndromes (24.2%). High titers of antibodies to toxocaras in 78.8% of patients are accompanied by severe peripheral blood eosinophilia. A 10-day course of albendazole in most patients (63.7%) leads to clinical and laboratory improvement with a decrease in the number of eosinophils and toxocara antibody titers. To achieve a favorable invasion level, three courses of treatment are recommended. The article presents a clinical case of toxocariasis in a patient five years old.

    Key words: children, toxocariasis, clinic, diagnosis, treatment.

    (For citation: Gilmullina F.S. Clinical and epidemiological features, diagnosis and treatment of toxocariasis in children. Practical Medicine. 2019. Vol. 17, № 8, P. 58-61)

     REFERENCES

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    2. Toksokaroz. Klinika. Diagnostika, Lechenie. Profilaktika. Informatsionno-metodicheskoe posobie [Toxocariasis. Clinic. Diagnosis, treatment. Prevention Informational-methodical manual]. Novosibirsk, 2004. 48 p.
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    5. Kholodnyak G.E. Kliniko-epidemiologicheskie osobennosti, diagnostika i novye podkhody k terapii toksokaroza u detey: avtoref. dis. … kand. med. nauk [Clinical and epidemiological features, diagnosis and new approaches to the treatment of toxocariasis in children. Synopsis of dis. PhD med. sciences]. Moscow, 2009. 25 p.
    6. Baum T.G., Pervishko O.V., Shashel’ V.A., Lupash N.G. Clinical and epidemiological features of toxocariasis in children. Kubanskiy nauchnyy meditsinskiy vestnik, 2017, vol. 24, no. 4, pp. 18-21 (in Russ.).

    Метки: 2019, Children, clinic, diagnosis, F.S. GILMULLINA, Practical medicine part 17 №8. 2019, toxocariasis, treatment

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