A.A. KAMALOVA¹, A.R. SHAKIROVA², G.A. GARINA¹

 ¹Kazan State Medical University, Kazan

²Children’s Republican Clinical Hospital, Ministry of Health of Republic of Tatarstan, Kazan

Contact details:

Kamalova A.A. — MD, Professor of the Department of Hospital Pediatrics

Address: 49 Butlerov St., Russian Federation, Kazan, 420012, tel.: +7 (843) 237-30-37, e-mail: aelitakamalova@gmail.com

Our knowledge of the clinical spectrum of celiac disease has expanded significantly in the recent decades. Today it is obvious that this common disease occurs at all ages and has clinical polymorphism. Along with the classical form of celiac disease, represented by malabsorption syndrome, atypical forms of the disease are increasingly common. Growth inhibition may be the only manifestation of celiac disease and it is mainly due to nutrient deficiencies. Prescription of gluten-free diet leads to a marked improvement in growth rates. In rare cases, improvement in growth rates does not occur. Then it is necessary to exclude other causes, including endocrine ones. The article presents modern data on the possible causes of growth inhibition in celiac disease. The review was illustrated by a clinical observation of a teenager with growth inhibition due to diagnosed hypopituitarism. Inefficiency of therapy and a thorough physical examination which showed gastrointestinal symptoms made it possible to suspect celiac disease and prescribe a gluten-free diet, which improved the patient’s growth.

Keywords: celiac disease, growth hormone deficiency, growth inhibition, hypopituitarism.

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