Biological therapy of severe bronchial asthma: organizational and clinical aspects, experience of organizing a specialized center
O.V. SKOROKHODKINA1, 2, R.A. SHAGVALIEVA3, E.V. DEMYANOVA2, A.V. BAGAUTDINOV2, A.V. LUNTSOV2, E.V. DYAKOVA2
1Kazan State Medical University of the Ministry of Health of the Russian Federation, Kazan
2Republic Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, Kazan
3Ministry of Health of the Republic of Tatarstan, Kazan
Contact details:
Skorokhodkina O.V. — MD, Professor, Head of the Department of Clinical Immunology with Allergology, Chief allergist-immunologist of the Ministry of Health of the Republic of Tatarstan
Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7 (843) 231-21-68, e-mail: olesya-27@rambler.ru
Severe bronchial asthma is a serious medical and social problem of modern healthcare. It is characterized by a significant decrease in the quality of life of patients, high disability rate, potential mortality, and existing difficulties in organizing medical care. In turn, biological therapy of severe bronchial asthma is a highly effective method of treatment that can qualitatively change the disease prognosis. Currently, the Republic of Tatarstan is implementing a model of providing specialized medical care for severe bronchial asthma by organizing a regional Center for biological therapy of severe bronchial asthma at the multidisciplinary medical institution «Republic Clinical Hospital of the Ministry of Health of the Republic of Tatarstan». The article provides data on the principles of the Center functioning and presents the results of the authors’ clinical experience in biological therapy of severe bronchial asthma.
Key words: severe bronchial asthma, biological therapy, Center for biological therapy.
REFERENCES
- Astma, informatsionnyy byulleten, VOZ, 2017 [Asthma. News bulletin. WHO. 2017], available at: http://www.who.int/ru/news-room/fact-sheets/detail/asthma (accessed on: 28.03.2021)
- Zabolevaemost’ vsego naseleniya Rossii v 2019 g. Statisticheskie materialy, Chast’ II. Ministerstvo zdravookhraneniya Rossiyskoy Federatsii, Departament monitoringa, analiza i strategicheskogo razvitiya zdravookhraneniya, FGBU «Tsentral’nyy nauchno-issledovatel’skiy institut organizatsii i informatizatsii zdravookhraneniya» Minzdrava Rossii [The incidence of the entire population of Russia in 2019 Statistical materials, Part II. Ministry of Health of the Russian Federation, Department of Monitoring, Analysis and Strategic Development of Health Care, Federal State Budgetary Institution «Central Research Institute for Organization and Informatization of Health Care» of the Ministry of Health of Russia]. Moscow, 2020. 142 p.
- Sotsial’no-ekonomicheskoe bremya bronkhial’noy astmy i khronicheskoy obstruktivnoy bolezni legkikh v Rossiyskoy Federatsii, pod red. V.V. Omel’yanovskogo [Socio-economic burden of bronchial asthma and chronic obstructive pulmonary disease in the Russian Federation, ed. by V.V. Omelyanovsky]. Moscow, 2009.
- Smertnost’ naseleniya po prichinam smerti v 2018 g., Rossiyskaya Federatsiya. Federal’naya sluzhba gosudarstvennoy statistiki [Mortality by causes of death in 2018, Russian Federation. Federal State Statistics Service], avaialvle at: www.gks.ru/free_doc/new_site/population/demo/demo24-2.xls (accessed on: 28.03.2021)
- Shvetsova E.S., Korotkova T.S. The prevalence of allergic diseases among all age groups of the population of the Lipetsk region. Sovremennye problemy nauki i obrazovaniya, 2017, no. 4 (in Russ.), available at: http://www.science-education.ru/ru/article/view?id=26724 (accessed on: 28.03.2021)
- Arkhipov V.V., Grigor’eva E.V., Gavrishina E.V. Control over bronchial asthma in Russia: results of a multicenter observational study of NIKA. Pul’monologiya, 2011, no. 6, pp. 87–93 (in Russ.).
- Bronkhial’naya astma. Klinicheskie rekomendatsii, 2019 [Bronchial asthma. Clinical guidelines, 2019], available at: https://spulmo.ru/upload/kr_bronhastma_2019.pdf (accessed on: 28.03.2021)
- Global’naya strategiya po lecheniyu i profilaktike bronkhial’noy astmy (GINA), 2020 [Global strategy for the treatment and prevention of bronchial asthma (GINA), 2020], available at: https://ginasthma.org/ (accessed on: 28.03.2021).
- GINA Pocket Guide, «Diagnosis and Management of Difficult-to-treat and Severe Asthma in adolescent and adult patients. V2.0, April 2019», available at: https://ginasthma.org/severeasthma/ (accessed on: 28.03.2021).
- Soglasitel’nyy doklad ob»edinennoy gruppy ekspertov TYaZhELAYa BRONKhIAL»NAYa ASTMA, 2018 [Consensus report of the joint expert group SEVERE BRONCHIAL ASTHMA, 2018], available at: http://www.science-education.ru/ru/article/view?id=26724 (accessed on: 28.03.2021)
- Emel’yanov A.V. Severe bronchial asthma. Astma i allergiya, 2013, no. 3, pp. 16–20 (in Russ.).