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  • Application of stromal vascular fraction cells from adipose tissue in the surgery of brachial plexus injuries

    Редактор | 2022, Practical medicine part 20 №6. 2022 | 20 ноября, 2022

    A.A. BOGOV1, I.G. KHANNANOVA1, I.F. AKHTYAMOV1, 4, V.I. DANILOV1, 2, A.A. BOGOV3

    1Republic Clinical Hospital, Kazan

    2Interregional Clinical Diagnostic Center, Kazan

    3Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan

    4Kazan State Medical University, Kazan

     Contact details:

    Bogov A.A. — researcher

    Address: Orenburgskiy trakt 138, Kazan, Russian Federation, 420064, tel.: +7-917-284-52-92, e-mail: bogov.jr@gmail.com

     The purpose — to evaluate the therapeutic properties of cells of the stromal vascular fraction isolated from adipose tissue of injuries of brachial plexus.

    Material and methods. The study was carried out on 62 patients using cells of the stromal vascular fraction and classical methods of treatment for brachial plexus injury. The efficiency of regeneration was assessed using electromyography and a positive recovery of motor and sensory functions.

    Results. Evaluation of the results of surgical treatment using cells of the stromal vascular fraction after neurolysis of the brachial plexus showed the restoration of early function of M3-M5 and S3–S4 in 90% of patients, and in the comparison group 68%. The number of patients with M4–M5 functions in the group with the use cells of the stromal vascular fraction for brachial plexus neurotization was 85%, while in the control group it was 64%. The ENMG study data also indicated an increase in the average number of motor units by 30% after the use of cells of the stromal vascular fraction, in contrast to the comparison group.

    Conclusion. Cells of the stromal vascular fraction from adipose tissue appear to be promising stimulators for the regeneration for recovery from trauma to the brachial plexus.

    Key words: brachial plexus injury, stromal vascular fraction cells from adipose tissue.

     REFERENCES

    1. Petrova D.Yu., Podgayskiy V.N., Nedz’ved’ M.K. The possibility of repairing damaged peripheral nerves during transplantation of mesenchymal stem cells. Mezhdunarodnye obzory: klinicheskaya praktika i zdorov’e, 2014, no. 4, pp. 5–7 (in Russ.).
    2. Kim I., Bang S.I., Lee S.K., Park S.Y., Kim M., Ha H. Clinical implication of allogenic implantation of adipogenic differentiated adipose-derived stem cells. Stem Cells Transl. Med., 2014, vol. 3 (11), pp. 1312–1321. DOI: 10.5966/sctm.2014-0109 25
    3. Stoltz J.F., de Isla N., Li Y.P., Bensoussan D., Zhang L., Huselstein C. et al. Stem cells and regenerative medicine: myth or reality of the 21th century. Stem Cells Int, 2015, vol. 734731, p. 19. DOI: 10.1155/2015/734731
    4. Johal K.S., Lees V.C., Reid A.J. Adipose-derived stem cells: selecting for translational success. Regen. Med, 2015, vol. 10 (1), pp. 79–96. DOI: 10.2217/rme.14.72 23
    5. Minteer D.M., Marra K.G., Rubin J.P. Adipose stem cells: biology, safety, regulation, and regenerative potential. Clin. Plast. Surg, 2015, vol. 42 (2), pp. 169–179. DOI: 10.1016/j.cps.2014.12.007 30
    6. Vapniarsky N., Arzi B., Hu J.C., Nolta J.A., Athanasiou K. Concise review: human dermis as an autologous source of stem cells for tissue engineering and regenerative medicine. Stem Cells Transl. Med, 2015, vol. 4 (10), pp. 1187–1198. DOI: 10.5966/sctm.2015-0084
    7. Watt F.M., Hogan B.L. Out of Eden: stem cells and their niches. Science, 2000, vol. 287 (5457), pp. 1427–1430. DOI: 10.1126/science.287.5457.1427
    8. Lopatina T., Kalinina N., Karagyaur M., Stambolsky D., Rubina K., Revischin A., Pavlova G., Parfyonova Y., Tkachuk V. PLoS One, 2011, vol. 14 (6), p. e17899.

    Метки: 2022, A.A. BOGOV, brachial plexus injury, I.F. AKHTYAMOV, I.G. KHANNANOVA, Practical medicine part 20 №6. 2022, stromal vascular fraction cells from adipose tissue, V.I. DANILOV

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