E.V. FAYZULLINA¹, A.R. USMANOV¹, D.N. GUBAYEVA¹, Yu.V. DAVYDOV¹, R.F. HAKIMOVA¹, R.G. KUZNETSOV²

¹Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

²Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064 

Fayzullina E.V. — D. Med. Sc., Professor of the Dermatology and Venereology Department, tel. +7-917-291-11-77, e-mail: [email protected]¹

Usmanova A.R. — 5^th year student of Medical Faculty, tel. +7-904-672-00-98, e-mail: [email protected]¹

Gubayeva D.N. — 5^th year student of Medical Faculty, tel. +7-952-048-69-80, e-mail: [email protected]¹

Davydov Yu.V. — postgraduate student of the Dermatology and Venereology Department, tel. +7-917-872-75-10, e-mail: [email protected]¹

Khakimova R.F. — D. Med. Sc., Professor of the Department of Clinical Immunology and Allergology, tel. +7-937-285-75-38, e-mail: [email protected]¹

Kuznetsova R.G. — Senior Researcher of Scientific-research Department, tel. (843) 237-34-47, e-mail: [email protected]² 

The article presents the results of the research of risk factors, aetiology and clinical manifestations of toxicodermia. 40 patients with toxicodermia were observed at the department of Allergology of Kazan State Clinical Hospital № 7 and the Department of Dermatology of the Clinical Dermatology and Venereology Dispensary of the Republic of Tatarstan. 40 people were observed as a control group. The influence of the gender, smoking, usage of medical substances and exposure to harmful chemicals was verified as statistically significant. The aetiology and clinical manifestation of the toxicodermia at different degrees of severity were analyzed.

Key words: toxicodermia, drug allergy, acute toxic allergic reaction.

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