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  • Analysis of risk factors, aetiology and clinical manifestations of toxicodermia

    Редактор | 2014, Practical medicine 04 (14) Innovative technologies in medicine. Part 1 | 30 июля, 2014

    E.V. FAYZULLINA1, A.R. USMANOV1, D.N. GUBAYEVA1, Yu.V. DAVYDOV1, R.F. HAKIMOVA1, R.G. KUZNETSOV2

    1Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

    2Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064 

    Fayzullina E.V. — D. Med. Sc., Professor of the Dermatology and Venereology Department, tel. +7-917-291-11-77, e-mail: [email protected]1

    Usmanova A.R. — 5th year student of Medical Faculty, tel. +7-904-672-00-98, e-mail: [email protected]1

    Gubayeva D.N. — 5th year student of Medical Faculty, tel. +7-952-048-69-80, e-mail: [email protected]1

    Davydov Yu.V. — postgraduate student of the Dermatology and Venereology Department, tel. +7-917-872-75-10, e-mail: [email protected]1

    Khakimova R.F. — D. Med. Sc., Professor of the Department of Clinical Immunology and Allergology, tel. +7-937-285-75-38, e-mail: [email protected]1

    Kuznetsova R.G. — Senior Researcher of Scientific-research Department, tel. (843) 237-34-47, e-mail: [email protected]2 

    The article presents the results of the research of risk factors, aetiology and clinical manifestations of toxicodermia. 40 patients with toxicodermia were observed at the department of Allergology of Kazan State Clinical Hospital № 7 and the Department of Dermatology of the Clinical Dermatology and Venereology Dispensary of the Republic of Tatarstan. 40 people were observed as a control group. The influence of the gender, smoking, usage of medical substances and exposure to harmful chemicals was verified as statistically significant. The aetiology and clinical manifestation of the toxicodermia at different degrees of severity were analyzed.

    Key words: toxicodermia, drug allergy, acute toxic allergic reaction.

     

     

    REFERENCES

    1. Kochergin N.V., Ivanov O.L. Skin disease syndrome drug. Terapevticheskikh arkhiv, 2005, no. 1, pp. 80-85 (in Russ.).

    2. Kravchun P.G., Shumova N.V., Babadzhan V.D., Zalyubovskaya E.I., Amer L.B. Toksikodermiya as a manifestation of drug allergy. Klinicheskaya immunologiya. Allergologiya. Infektologiya, 2013, no. 2 (Spetsvypusk) (in Russ.).

    3. Ivanov O.L. Spravochnik “Kozhnye i venericheskie bolezni” [Directory “Skin and venereal disease”]. Moscow, 2013. 351 p.

    4. Fayzullina E.V., Davydov Yu.V., Usmanova A. R., Gubaeva D.N. Analiz faktorov riska, etiologii i klinicheskikh proyavleniy toksidermii [Analysis of risk factors, etiology and clinical manifestations of drug reaction]. Yubileynaya Vserossiyskaya mezhdistsiplinarnaya nauchno-prakticheskaya konferentsiya “Infektsiya, peredavaemaya polovym putem i reproduktivnoe zdorov’e naseleniya. Sovremennye metody diagnostiki i lecheniya dermatozov”, posvyashchennaya 200-letiyu Kaz. gos. med. universiteta. Kazan, 25 marta, 2014. Pp. 152-158 (in Russ.).

    5. Berenbeyna B.A., Studnitsina A.A. Differentsial’naya diagnostika kozhnykh bolezney. Ruk-vo dlya vrachey. 2-e izd. [Differential diagnosis of skin diseases. Hands of physicians. 2nd ed.] Moscow, 1989. Pp. 105-171.

    6. Kochergin N.G., Shvetsov O.L. Ter. arkhiv, 2005, vol. 77, no. 1, pp. 80-81.

    7. Kochergin N.G., Kochergin S.N. Indices symptom scores and quality of life in dermatology. Materialy VIII Vseros. S»ezda dermatovenerologov. Moscow, 2001. Part. 1. Pp. 148-149.

    8. de la Torre C., Suh Oh H.J. Advances in the diagnosis of drug eruptions. Actas dermo-sifiliograficas, 2013, 104 (9). Pp. 782-8.

    Метки: A.R. USMANOV, acute toxic allergic reaction, D.N. GUBAYEVA, drug allergy, E.V. FAYZULLINA, Practical medicine 04 (14) Innovative technologies in medicine. Part 1, R.F. HAKIMOVA, R.G. KUZNETSOV, toxicodermia, Yu.V. DAVYDOV

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