R.N. MAMLEEV^1, 2, A.V. SINCHUGOV², R.M. ASADULLINA¹

¹Kazan State Medical University, Kazan

²Children’s Republican Clinical Hospital, Ministry of Health of Republic of Tatarstan, Kazan

Contact details:

Mamleev R.N. — PhD (medicine), Associate Professor of Department of Hospital Pediatrics

Address: 49 Butlerov St., Russian Federation, Kazan, 420012, tel.: +7-917-921-12-70, e-mail: [email protected]

 Genetically determined diseases, Alport syndrome in particular, are traditionally the object of polypharmacy. The addition of intercurrent infection aggravates this situation, since it requires comedication directed at the focus of infection. Multiple drug interactions, which lead to a weakening of the therapeutic effect of some drugs and increase the toxic potential of others, require attention from all participants of the therapeutic process.

Key words: Alport syndrome, acute otitis externa, polypharmacy.

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