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  • Agranulocytosis with thyreostatic therapy in a teenage girl

    Редактор | 2016, Practical medicine 07 (16) Actual problems of pediatrics | 24 ноября, 2016

    N.V. KRINITSKAYA1, O.G. PECHERITSA1, M.R. SHAIDULLINA1,2, Yu.V. ISKHAKOVA1

    1Children Republic Clinical Hospital, 140 Orenburgskiy Trakt, Kazan, Russian Federation, 420138

    2Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012

     Krinitskaya N.V. — Head of Endocrinology Department, tel. (843) 237-30-05, e-mail: Natalya.Krinickaya@tatar.ru

    Pecheritsa O.G. — Cand. Med. Sc., doctor of Endocrinology Department, tel. (843) 237-30-05, e-mail: Oksana.Pecherica@tatar.ru

    Shaidullina M.R. — Cand. Med. Sc., doctor of Endocrinology Department, Associate Professor of the Department of Endocrinology, tel. (843) 237-30-05, e-mail: zizi97@mail.ru

    Iskhakova Yu.V. — doctor of Endocrinology Department, tel. (843) 237-30-05, e-mail: julii70@mail.ru

    This article describes a case of agranulocytosis in a teenage girl with diffuse toxic goiter under the background of conservative thyreostatic therapy with Thiamazolum, which significantly complicated the hyperthyroidism compensation in the patient. The tactics of eliminating the life-threatening condition and difficulties of choosing the further therapy method are described.

    Key words: agranulocytosis, hyperthyroidism, thyreostatic therapy, goiter

    REFERENCES

    1. Distenfeld A., Seiter K., Talavera F., Guthrie T. Jr, McKenna R., Besa E. Agranulocytosis, June 26, 2003, available at: www.eMedicine.com
    2. Atamanov V.M., Demicheva T.P. Cytopenia and hyperthyroidism. Problemy gematologii i perelivaniya krovi, 2003, no. 4, pp. 33-34 (in Russ.).
    3. Vanushko V.E., Fadeev V.V. Graves’ disease (clinical lecture). Endokrinnaya khirurgiya, 2013, no. 1, pp. 23-33 (in Russ.).
    4. Bahn R.S., Burch H.B., Cooper D.S., Garber J.R., Greenlee M.C. et al. Hyperthyroidism and Other Causes of Thyrotoxicosis: Management Guidelines of the America n Thyroid Association and America n Association of Clinical Endocrinologists. Thyroid, 2011, Vol. 21.
    5. Troshina E.A., Sviridenko N.Yu., Vanushko V.E. et al. Federal’nye klinicheskie rekomendatsii po diagnostike i lecheniyu tireotoksikoza s diffuznym zobom [Federal guidelines for the diagnosis and treatment of hyperthyroidism with diffuse goiter]. Moscow: Praktika, 2014. 25 p.
    6. Dedov I.I., Peterkova V.A. Federal’nyy klinicheskie rekomendatsii (protokoly) po vedeniyu detey s endokrinnymi zabolevaniyami [Federal clinical guidelines (protocols) on the management of children with endocrine diseases]. Moscow: Praktika, 2014. Pp. 215-239.

    Метки: 2016, agranulocytosis, goiter, hyperthyroidism, M.R. SHAIDULLINA, N.V. KRINITSKAYA, O.G. PECHERITSA, Practical medicine 07 (16) Actual problems of pediatrics, thyreostatic therapy, Yu.V. ISKHAKOVA

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