E.M. SPERANSKAYA¹, L.I. NIKITINA¹, N.N. GOLUBTSOVA¹, L.R. MUKHAMEDZHANOVA^1,2, R.G. KUZNETSOVA³

¹Chuvash State University named after I.N. Ulyanov, 15 Moskovskiy Prospekt, Cheboksary, Russian Federation, 428015

²Educational and Methodological Center «Eksklyuziv-Dent», 42 Kosmonavtov St., Kazan, Russian Federation, 420099

³Republican Clinical Hospital of Ministry of Health of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064 

Speranskaya E.M. — 5-year student of the Medical Faculty, tel. +7-917-662-93-53, e-mail: katerina_dumspirospero@mail.ru¹

Nikitina L. I. — Cand. Med. Sc., Associate Professor, Head of Department of Stomatology Diseases Propaedeutics and New Technologies, tel. +7-903-359-38-29, e-mail: president-clinik@mail.ru¹

Golubtsova N.N. — Cand. Med. Sc., Associate Professor of the Department of Cytology, Histology and Embryology, tel. +7-903-675-26-22, e-mail: president-clinik@mail.ru¹

Mukhamedzhanova L.R. — D. Med. Sc., Professor of Department of Propaedeutics of Stomatology Diseases and New Technologies, tel. +7-965-597-11-64, e-mail: lr71@bk.ru^1,2

Kuznetsova R.G. — Senior Researcher of the Scientific-Research Department, tel. (843) 237-34-47, e-mail: rokuz@mail.ru³ 

The content of catecholamines, histamine and serotonin in the connective tissue of periodontal structures in patients with inflammatory-destructive periodontal disease has been studied. It was found that neyroamines accumulation in association with generalized periodontitis leads to changes of cytoarchitectonics and hemomicrocirculation. An association between the degree of accumulation of catecholamines, histamine and serotonin and the severity of histological lesions of periodontal tissue structures has been shown.

Key words: inflammatory and destructive periodontal lesions, catecholamines, histamine, serotonin.

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