8-Iso-prostaglandin level and its relation to metabolic parameters in patients with type 2 diabetes mellitus in combination with non-alcoholic fatty liver disease
E.G. DOROSH, N.A. KRAVCHUN
V. Danilevsky Institute of Endocrine Pathology Problems of National Academy of Medical sciences of the Ukraine, 10 Artema St., Kharkov, the Ukraine 61002
Dorosh E.G. — graduate student of Department of pharmacotherapy of endocrine diseases, tel. +38057-315-11-88, e-mail: dorosh84@ukr.net1
Kravchun N.A. — D. med. Sc., Professor, Deputy Director for Science, Head of the Department of pharmacotherapy of endocrine diseases, tel. +38057-315-44-56, e-mail: kravchunna@mail.ru1
The article studies 8—Iso—prostaglandin level and its relation to metabolic parameters in the patients with type 2 diabetes mellitus (DM) combined with non-alcoholic fatty liver disease (NAFLD). The role of the main indicator of oxidative stress 8-Iso-prostaglandin in NAFLD formation which may be a diagnostic marker of endothelial dysfunction and atherogenesis has been established.
Key words: 8—Iso—prostaglandin, type 2 diabetes mellitus, non-alcoholic fatty liver disease, oxidative stress, lipid peroxidation.
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